{"id":"W1987157611","doi":"10.1021/bi900184j","title":"Peptide Models of Membrane Protein Folding","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Membrane protein; Transmembrane protein; Folding (DSP implementation); Computational biology; Peptide; Protein folding; Peptide sequence; Helix (gastropod); Membrane; Biochemistry; Transmembrane domain; Rational design; Amino acid; Biology; Chemistry; Biophysics; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007397998,0.0001650441,0.0001612862,0.00001512543,0.00003558802,0.000009920115,0.0002174666,0.0001927548,0.00002713363],"category_scores_gemma":[0.00002963148,0.000154915,0.0001227887,0.00007138339,0.0000509118,0.000004140754,0.00004203563,0.00007726254,0.000001821632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009567269,"about_ca_system_score_gemma":0.00007645572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000479842,"about_ca_topic_score_gemma":5.482261e-7,"domain_scores_codex":[0.9991024,0.00001089598,0.0002157158,0.0003094444,0.0001466224,0.0002149014],"domain_scores_gemma":[0.9993366,0.000002228192,0.00009329871,0.000415044,0.00007084196,0.00008199138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005045703,0.00004901567,0.00003607682,0.000044246,0.00001351682,0.000002168856,0.00001154778,0.00002083602,0.9977636,0.00008456899,0.0003113449,0.001612657],"study_design_scores_gemma":[0.0003571621,0.000122627,0.00008526701,0.00003230527,0.00002017907,0.00001734759,0.00002418999,0.00002504361,0.9984154,0.0001214998,0.0005947753,0.0001842036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922634,0.0001814338,0.000200811,0.00007700297,0.00004511714,0.0001385856,0.00001824262,0.00001811633,0.007057301],"genre_scores_gemma":[0.9958132,0.00001698098,0.001572359,0.00009828443,0.0003085707,0.000008938016,0.0000863574,0.00001395408,0.002081381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004975919,"threshold_uncertainty_score":0.631725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01019910738718532,"score_gpt":0.2388456244807193,"score_spread":0.228646517093534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}