{"id":"W1987191514","doi":"10.1172/jci57850","title":"The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies","year":2011,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; McMaster University; Canadian Blood Services; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; Canadian Blood Services; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Antibody; Platelet; Immunology; Immune system; Medicine; Fetus; Miscarriage; Biology; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017505,0.0001514272,0.0005177628,0.00009356911,0.0000847702,0.00004045339,0.0001194787,0.0001253099,0.00002043237],"category_scores_gemma":[0.0006982209,0.00009517634,0.0001106579,0.0001006563,0.0002068858,0.0001252944,0.00002679458,0.0003717758,0.000002652295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000474218,"about_ca_system_score_gemma":0.0001591991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004473595,"about_ca_topic_score_gemma":0.000167972,"domain_scores_codex":[0.9979116,0.0004114551,0.001023533,0.0001584239,0.0002903386,0.0002046554],"domain_scores_gemma":[0.9984711,0.0004717398,0.000550814,0.000140886,0.00009885713,0.0002666354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01990234,0.00150544,0.7634515,0.00007999815,0.001558067,0.002951257,0.01059561,0.000007308602,0.1652793,0.00007018649,0.002164407,0.03243455],"study_design_scores_gemma":[0.004709105,0.00179786,0.9425867,0.0003525136,0.00011987,0.0005894993,0.0005788463,0.00002729562,0.04695546,0.001277882,0.0008797226,0.0001252591],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910886,0.001152442,0.00001189107,0.0071382,0.0002469416,0.0003038655,0.00001730578,0.000007865587,0.00003285757],"genre_scores_gemma":[0.9971888,0.001077863,0.0006017165,0.0009030051,0.00006027493,0.000005096733,0.000007541056,0.00001697952,0.0001387236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1791352,"threshold_uncertainty_score":0.3881178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06504925598589575,"score_gpt":0.3337675421817897,"score_spread":0.268718286195894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}