{"id":"W1987208122","doi":"10.1371/journal.pone.0068213","title":"Evolution of Primary HIV Drug Resistance in a Subtype C Dominated Epidemic in Mozambique","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Public Health Agency of Canada","funders":"U.S. Public Health Service; Centers for Disease Control and Prevention; Universidade Federal do Rio de Janeiro; Ministério da Educação; Public Health Agency; U.S. Department of Health and Human Services; Public Health Agency of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; U.S. President’s Emergency Plan for AIDS Relief","keywords":"Drug resistance; Subtyping; HIV drug resistance; Virology; Nucleoside Reverse Transcriptase Inhibitor; Reverse transcriptase; Antiretroviral treatment; Lopinavir; Human immunodeficiency virus (HIV); Biology; Reverse-transcriptase inhibitor; Medicine; Antiretroviral therapy; Viral load; Genetics; Polymerase chain reaction; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003118659,0.0002843742,0.0002637614,0.0008748752,0.0008063475,0.000874027,0.0002598384,0.0003461127,0.0008471959],"category_scores_gemma":[0.0007136678,0.0001849511,0.0002242525,0.001061259,0.0004449496,0.0002013948,0.0003274397,0.0003556571,0.00008592188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00179026,"about_ca_system_score_gemma":0.001285713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.1970305,"about_ca_topic_score_gemma":0.1641181,"domain_scores_codex":[0.9997961,0.00003321777,0.000007199827,0.00003653718,0.00001646532,0.000110616],"domain_scores_gemma":[0.9997657,0.00003044313,0.0000830037,0.00001276574,0.00005756071,0.0000505938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003006613,0.00005274604,0.9825075,0.00005794898,0.00007702395,0.001069194,0.001676341,0.0005029809,0.007441328,0.0001419864,0.0004064734,0.005765828],"study_design_scores_gemma":[0.0000100733,0.00004205678,0.9982263,0.00001051264,0.00001133742,0.0002332444,0.0006879758,0.0004471297,0.00007733663,0.00001539402,0.0002339211,0.000004719445],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995153,0.00007576816,0.00002888668,0.00002982639,8.080984e-7,0.00001016455,0.0001238538,0.000003330478,0.0002121154],"genre_scores_gemma":[0.9994455,0.0000954855,0.0001244519,0.00002173573,0.00000213119,0.00001050502,0.0001957487,0.000001307433,0.0001030191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1970305,"threshold_uncertainty_score":0.3917673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721150096168966,"score_gpt":0.2144024032771523,"score_spread":0.1971909023154627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}