{"id":"W1987223696","doi":"10.1016/s0166-3542(02)00100-6","title":"Polymorphisms of cytotoxic T-lymphocyte (CTL) and T-helper epitopes within reverse transcriptase (RT) of HIV-1 subtype C from Ethiopia and Botswana following selection of antiretroviral drug resistance","year":2002,"lang":"en","type":"article","venue":"Antiviral Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"CTL*; Virology; Reverse transcriptase; Cytotoxic T cell; Epitope; Human immunodeficiency virus (HIV); Drug resistance; Biology; Antiretroviral drug; Lentivirus; Immunology; Viral load; Viral disease; Antiretroviral therapy; Antibody; Polymerase chain reaction; Genetics; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009333127,0.0001846947,0.0005098043,0.0003325554,0.0002081461,0.00001468946,0.0001916885,0.0002004513,0.0001328882],"category_scores_gemma":[0.0002629071,0.0001602663,0.0001180979,0.0004508964,0.0009286746,0.0002078301,0.00009360004,0.0004583416,0.00005057763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007790962,"about_ca_system_score_gemma":0.0001208593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004151367,"about_ca_topic_score_gemma":0.0005018141,"domain_scores_codex":[0.9975855,0.0007817819,0.0004471257,0.0004231601,0.0002572765,0.0005051459],"domain_scores_gemma":[0.9989758,0.000400783,0.000131097,0.0002819808,0.0001636958,0.00004667597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009496883,0.0002127878,0.05195754,0.0001005197,0.0002896588,0.00003392332,0.001871199,1.188088e-7,0.9403689,0.0003318461,0.001571315,0.002312503],"study_design_scores_gemma":[0.003430251,0.0007562123,0.02842531,0.0002617865,0.00006021167,0.000006215318,0.000519349,0.00002574807,0.9653943,0.000189032,0.0007700151,0.0001615903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847454,0.01375746,0.00001235866,0.0002321672,0.00007816254,0.0003389255,0.0003095839,0.00001381461,0.0005121556],"genre_scores_gemma":[0.9930099,0.001775959,0.0002791781,0.000009617049,0.00001335214,0.00001121628,0.00006182839,0.00001961762,0.004819277],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02502538,"threshold_uncertainty_score":0.653547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03245605493870297,"score_gpt":0.2868322076955744,"score_spread":0.2543761527568714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}