{"id":"W1987248079","doi":"10.1016/j.biocel.2014.09.021","title":"Dynamin 2 interacts with connexin 26 to regulate its degradation and function in gap junction formation","year":2014,"lang":"en","type":"article","venue":"The International Journal of Biochemistry & Cell Biology","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital; Western University","funders":"Canadian Cancer Society; Canadian Breast Cancer Research Alliance; University of British Columbia; University of Guelph; Breast Cancer Alliance; Mayo Clinic","keywords":"Endocytic cycle; Dynamin; Cell biology; Endocytosis; Biology; Ubiquitin; Connexin; GTPase; Gap junction; Effector; GTPase-activating protein; CDC42; Intracellular; Endosome; Signal transduction; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003171476,0.0003441236,0.0003209794,0.0003260228,0.0005433378,0.0007208672,0.0002922617,0.000372477,0.001894754],"category_scores_gemma":[0.0002131953,0.0003222699,0.0004192597,0.0001619213,0.0003057673,0.0006218958,0.000532333,0.0005800115,0.0008050277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008827144,"about_ca_system_score_gemma":0.0003229577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005107503,"about_ca_topic_score_gemma":0.0009949052,"domain_scores_codex":[0.9997845,0.00002518923,0.00002052069,0.00006836069,0.00003711556,0.00006432362],"domain_scores_gemma":[0.9998052,0.00001694246,0.00007064653,0.00002034666,0.00002085974,0.00006602524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003746509,0.00003521514,0.0007351826,0.0000411468,0.00001393688,0.000237977,0.00002349456,0.0002021849,0.99654,0.0007121059,0.000157854,0.0009263847],"study_design_scores_gemma":[0.00004180691,0.00009366927,0.02050795,0.000009458347,0.00002028725,0.000631439,0.0000824936,0.00398889,0.9683927,0.0004550382,0.005755061,0.00002123344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908231,0.003126242,0.00326995,0.0002052373,0.0001109735,0.0000165916,0.0002321287,0.00006455307,0.002151091],"genre_scores_gemma":[0.9912684,0.0007179614,0.001444236,0.0000604559,0.00001411369,0.00002101887,0.0003633572,0.00003585985,0.006074576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001894754,"threshold_uncertainty_score":0.006404579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007361224908024602,"score_gpt":0.2289681435247206,"score_spread":0.221606918616696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}