{"id":"W1987269574","doi":"10.1158/0008-5472.can-08-0343","title":"Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":259,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; St. Paul's Hospital; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"Cancer Research Society","keywords":"Focal adhesion; Cell migration; Tyrosine phosphorylation; Phosphorylation; RHOA; Proto-oncogene tyrosine-protein kinase Src; Cancer research; Metastasis; Cell biology; Biology; Caveolin 1; Signal transduction; Cell; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002436,0.0001642162,0.0001166719,0.0002289188,0.0001686127,0.000257864,0.0001515344,0.0001689096,0.0006851214],"category_scores_gemma":[0.000167032,0.0001248406,0.0001167326,0.00009483239,0.0002455628,0.0001667289,0.0001408052,0.0002215503,0.0001809696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004626325,"about_ca_system_score_gemma":0.0002543484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027251,"about_ca_topic_score_gemma":0.001359868,"domain_scores_codex":[0.9999148,0.00001331917,0.000002990661,0.00001427159,0.00001666035,0.00003802174],"domain_scores_gemma":[0.999931,0.0000112829,0.00002322319,0.000004046461,0.000008696605,0.00002180014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002449705,0.00003764783,0.001664073,0.00003467851,0.000007177043,0.0001267584,0.00002474952,0.0001767829,0.9933755,0.0004399368,0.000161662,0.003705947],"study_design_scores_gemma":[0.00008788695,0.0003250921,0.1455679,0.0000192282,0.00003913716,0.001227799,0.0001143168,0.007803562,0.8394291,0.0008117512,0.004551411,0.00002274351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960168,0.001667064,0.0006816307,0.0001045227,0.000008265418,0.000006714094,0.00004448951,0.00004095245,0.001429619],"genre_scores_gemma":[0.9983571,0.0004540711,0.000266325,0.00001780082,0.000004337669,0.000006749763,0.0000699341,0.000006405343,0.0008173845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001027251,"threshold_uncertainty_score":0.003356695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02413126912354954,"score_gpt":0.2932387752233475,"score_spread":0.269107506099798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}