{"id":"W1987299162","doi":"10.1155/2011/461304","title":"Multiple Sclerosis: A Disorder of Altered T-Cell Homeostasis","year":2011,"lang":"en","type":"article","venue":"Multiple Sclerosis International","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Homeostasis; Multiple sclerosis; Pathogenesis; T-cell receptor; Autoimmunity; T cell; Thymic involution; Immunology; Medicine; Neuroscience; Biology; Cell biology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001840192,0.0003430232,0.00043585,0.0002951338,0.0001658921,0.00001903099,0.0008514413,0.0003532578,0.00306943],"category_scores_gemma":[0.0001167995,0.0003255565,0.00027883,0.0001782205,0.0004731051,0.0002068494,0.0002759304,0.0003548072,0.0008680662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006449976,"about_ca_system_score_gemma":0.0000428684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008829115,"about_ca_topic_score_gemma":0.0001941728,"domain_scores_codex":[0.9980588,0.0001417,0.0006905322,0.0004936153,0.0001110181,0.0005043611],"domain_scores_gemma":[0.9987587,0.0002083604,0.0002863827,0.0004817254,0.0002213143,0.00004354502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003451498,0.001091012,0.04613887,0.0000195122,0.0003807547,0.000001040222,0.0009917143,0.00002173315,0.9366486,0.0001343021,0.002786962,0.01144035],"study_design_scores_gemma":[0.006248498,0.0002290522,0.07517467,0.00009847742,0.00005896149,0.00001132337,0.0005509896,0.0002381849,0.9043899,0.0001176879,0.01245982,0.0004224458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868599,0.002988457,0.001117421,0.0001016433,0.00354852,0.0003230762,0.0004149207,0.0001790899,0.004466968],"genre_scores_gemma":[0.995575,0.0009282619,0.001683195,0.0001213355,0.00006331478,0.00009413762,0.0003043207,0.00004839096,0.001182038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03225872,"threshold_uncertainty_score":0.9999197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.064728533625021,"score_gpt":0.2239490782826024,"score_spread":0.1592205446575814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}