{"id":"W1987311941","doi":"10.1016/j.coi.2011.08.001","title":"Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter","year":2011,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":230,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Interferon; Innate immune system; Cell biology; Signal transducing adaptor protein; Signal transduction; Interferon type I; Mitochondrion; Endoplasmic reticulum; RIG-I; Virology; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006004145,0.0009900932,0.001276701,0.0006136309,0.0002287135,0.00141757,0.001121619,0.001698568,0.001601037],"category_scores_gemma":[0.0002964216,0.0002356997,0.0003436666,0.0007338697,0.0007610904,0.002173032,0.001176348,0.002577881,0.002270682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009109257,"about_ca_system_score_gemma":0.0007527557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003011967,"about_ca_topic_score_gemma":0.0006334628,"domain_scores_codex":[0.9998097,0.0000247733,0.00002029308,0.00004018217,0.00006948964,0.00003569023],"domain_scores_gemma":[0.9998154,0.00003900767,0.00005537002,0.000007328661,0.00004182132,0.00004106373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002658248,0.00006595376,0.0003719888,0.005962141,0.00008598941,0.0004844558,0.00007923847,0.0007229546,0.08058833,0.0178684,0.03496234,0.8585423],"study_design_scores_gemma":[0.00005308964,0.00008749781,0.001455478,0.0007989718,0.00008964643,0.001104266,0.0001197432,0.000634941,0.01497126,0.009091477,0.9715562,0.00003736809],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001293888,0.9914945,0.001819531,0.001738234,0.001291441,0.00001036251,0.00004675357,0.00005749329,0.002247724],"genre_scores_gemma":[0.007192275,0.9867091,0.00129929,0.0009060178,0.001141967,0.00001726516,0.0001422103,0.000008982497,0.002582883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001698568,"threshold_uncertainty_score":0.006609261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1245267581331939,"score_gpt":0.3715635265614839,"score_spread":0.2470367684282901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}