{"id":"W1987323109","doi":"10.1016/j.yjmcc.2012.11.019","title":"Structural and functional insights into the cardiac Na+/H+ exchanger","year":2012,"lang":"en","type":"review","venue":"Journal of Molecular and Cellular Cardiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Ingenuity; Heart and Stroke Foundation of Canada","keywords":"Sodium–hydrogen antiporter; Transmembrane protein; Transmembrane domain; Chemistry; Biophysics; Amino acid; Gene isoform; Lipid bilayer; Bilayer; Intracellular pH; Antiporter; Cytosol; Membrane; Cell biology; Biochemistry; Intracellular; Biology; Sodium; Gene; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006541624,0.0009055949,0.001382053,0.001291692,0.0002332059,0.001048321,0.0008597854,0.0009498296,0.002380845],"category_scores_gemma":[0.0004762929,0.0003406261,0.0004097479,0.001316473,0.0008306733,0.00234231,0.0008149457,0.001983491,0.001761442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004692189,"about_ca_system_score_gemma":0.0009512129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004514739,"about_ca_topic_score_gemma":0.0007817981,"domain_scores_codex":[0.9999,0.00001232353,0.00001867011,0.0000235933,0.00003328119,0.00001213833],"domain_scores_gemma":[0.9997705,0.0001005628,0.00003635363,0.000007721858,0.00006036742,0.00002453002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002151026,0.0001082783,0.0002415412,0.01543414,0.000100241,0.0004793218,0.0000860177,0.0006966673,0.01545377,0.008739403,0.01500324,0.9434422],"study_design_scores_gemma":[0.00004183254,0.0001759,0.00114738,0.001701819,0.0001806181,0.002028,0.0001010532,0.000340896,0.00362142,0.006691515,0.9839292,0.00004038345],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002988592,0.9978733,0.0004240788,0.0004020878,0.0001944324,0.000002709524,0.00001491282,0.000006324188,0.0007832687],"genre_scores_gemma":[0.001104704,0.9974943,0.0003514094,0.0001925735,0.0002500354,0.000002818988,0.00002816987,0.000001355133,0.0005745862],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002380845,"threshold_uncertainty_score":0.00796473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890179224798292,"score_gpt":0.2546062994118993,"score_spread":0.2357045071639164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}