{"id":"W1987371412","doi":"10.1016/j.mehy.2009.08.019","title":"Calcium channel as a potential anticancer agent","year":2009,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Regional Health Centre; McGill University Health Centre; Royal Victoria Hospital","funders":"","keywords":"Calcium; Extracellular; Calcium in biology; Intracellular; Apoptosis; Calcium channel; T-type calcium channel; Programmed cell death; Cancer cell; Cell biology; Chemistry; Cell; Necrosis; Cancer research; Biology; Biochemistry; Cancer; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001440215,0.0001009673,0.00009563896,0.00003187904,0.00006670835,0.00001508798,0.0001113968,0.0001675402,0.0006870439],"category_scores_gemma":[0.0002936902,0.00008275325,0.00007896295,0.00006089847,0.00006941087,0.000002664328,0.00002826577,0.0000723203,0.00009781062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009411933,"about_ca_system_score_gemma":0.00007237987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009877284,"about_ca_topic_score_gemma":0.000002122677,"domain_scores_codex":[0.9990563,0.00003643298,0.000136973,0.0002216228,0.0003507563,0.0001978473],"domain_scores_gemma":[0.9995838,0.000007049763,0.00003174094,0.0001507145,0.00004768761,0.0001789987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0014451,0.001499343,0.0004483506,0.00005334228,0.0002368114,0.0002477506,0.0003666546,0.0007659349,0.3824233,0.003700402,0.1505102,0.4583029],"study_design_scores_gemma":[0.002898054,0.002151046,0.01417949,0.00009070752,0.00005906014,0.0003291349,0.0002952376,0.007408029,0.3528456,0.004161125,0.6147237,0.0008588143],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8887143,0.001164486,0.07689953,0.01326286,0.002746363,0.0003476549,0.00001159687,0.0001045154,0.01674872],"genre_scores_gemma":[0.9907286,0.0001426966,0.00004964396,0.004486518,0.0015451,0.000006899861,0.00003382911,0.000009495949,0.002997209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4642135,"threshold_uncertainty_score":0.7522649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02184909212273163,"score_gpt":0.2828623325104797,"score_spread":0.261013240387748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}