{"id":"W1987377609","doi":"10.1016/j.str.2014.11.018","title":"Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile","year":2015,"lang":"en","type":"article","venue":"Structure","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Brookhaven National Laboratory; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Consejo Nacional de Ciencia y Tecnología; National Institutes of Health; Alberta Glycomics Centre","keywords":"Pilus; Pilin; Fimbriae Proteins; Microbiology; Biology; Biofilm; Clostridium difficile; Bacterial adhesin; Bacteria; Fimbria; Protein subunit; Horizontal gene transfer; Gene; Genetics; Escherichia coli; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001730148,0.0002697838,0.000229489,0.0007249798,0.0005132525,0.0004525643,0.0002682676,0.0003501754,0.001190361],"category_scores_gemma":[0.000526586,0.0001282759,0.0003602142,0.0006905342,0.000274092,0.0002618453,0.0003176611,0.0005216584,0.0002576831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004579653,"about_ca_system_score_gemma":0.0003488624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002236084,"about_ca_topic_score_gemma":0.003395244,"domain_scores_codex":[0.999886,0.00001558403,0.000007798032,0.00002020934,0.00002866642,0.00004184486],"domain_scores_gemma":[0.9997461,0.00005707996,0.00008593596,0.000029404,0.00004289786,0.00003848406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007772737,0.0001490978,0.0490454,0.000158384,0.00008420587,0.0005315294,0.000445917,0.005430972,0.9139904,0.002591942,0.0005865335,0.02620826],"study_design_scores_gemma":[0.00006877563,0.001142803,0.6579475,0.00009860667,0.0003384642,0.003039963,0.002119889,0.04215617,0.2771682,0.003062846,0.01274797,0.0001088476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975237,0.0002679735,0.001284519,0.00006629197,0.000005707343,0.000004343822,0.0001291713,0.00002061304,0.0006976363],"genre_scores_gemma":[0.9984492,0.000106597,0.0008061191,0.00002514793,0.000003803101,0.000003463796,0.0003238969,0.00001008827,0.0002715813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002236084,"threshold_uncertainty_score":0.004446089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06939233680364758,"score_gpt":0.3591930767362646,"score_spread":0.289800739932617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}