{"id":"W1987408537","doi":"10.1021/jp809116n","title":"Thermodynamic Role of Glutathione Oxidation by Peroxide and Peroxybicarbonate in the Prevention of Alzheimer’s Disease and Cancer","year":2009,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry A","topic":"Free Radicals and Antioxidants","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Redox; Conformational isomerism; Molecule; Exothermic reaction; Intramolecular force; Chirality (physics); Crystallography; Stereochemistry; Computational chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001881977,0.00008946487,0.0001879444,0.000007853079,0.00002610609,0.000007318144,0.000149651,0.00003264425,0.00001707559],"category_scores_gemma":[0.00002825882,0.00005182527,0.00006763213,0.00005644638,0.0001306998,0.00006920595,0.00001614931,0.0001883495,4.798214e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001062111,"about_ca_system_score_gemma":0.00003101808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001559942,"about_ca_topic_score_gemma":6.370142e-7,"domain_scores_codex":[0.999332,0.00003376794,0.0002500028,0.00007136582,0.0002240671,0.00008887289],"domain_scores_gemma":[0.9994251,0.00006886308,0.0003034068,0.0001135489,0.00003853396,0.00005060181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001268667,0.0003216814,0.00006243339,0.00005499045,0.00003506711,0.00000116864,0.0003886935,0.00004444046,0.9932356,0.00003567462,0.000009546726,0.005683846],"study_design_scores_gemma":[0.0007934347,0.00007340076,0.00852793,0.0003168948,0.000281361,0.00001650272,0.0004304009,0.007688727,0.9767827,0.00498284,0.00001679806,0.00008902625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946512,0.004619105,0.000008776509,0.0004288556,0.000001733007,0.00003034899,0.00001333808,0.000001888594,0.0002447295],"genre_scores_gemma":[0.9993551,0.0005263288,0.000005353708,0.00001669086,0.00007137098,0.000001178378,0.000002199198,0.000004938105,0.00001684648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01645291,"threshold_uncertainty_score":0.2113373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007222545272652292,"score_gpt":0.2500132829962614,"score_spread":0.2427907377236091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}