{"id":"W1987427709","doi":"10.1038/gt.2008.40","title":"Taming the Trojan horse: optimizing dynamic carrier cell/oncolytic virus systems for cancer biotherapy","year":2008,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa","funders":"","keywords":"Oncolytic virus; Trojan horse; Biology; Virus; In vivo; Ex vivo; Virology; Computer science; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006697309,0.00102762,0.001589517,0.0002145959,0.0006170892,0.0001539414,0.001453528,0.0008079139,0.00005346176],"category_scores_gemma":[0.00001463906,0.0007151164,0.001191136,0.0004211153,0.0002634025,0.000008695089,0.0001105541,0.0005047087,0.00001779743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003229884,"about_ca_system_score_gemma":0.001492752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001512695,"about_ca_topic_score_gemma":0.0001081808,"domain_scores_codex":[0.9956673,0.0006711711,0.0008507657,0.001204646,0.000492261,0.001113868],"domain_scores_gemma":[0.997233,0.0001268546,0.0005699297,0.001678248,0.0002111505,0.0001807925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001113429,0.0001261892,6.653835e-7,0.001442945,0.001515945,0.000009219583,0.0002800838,0.0006725655,0.07181649,0.000002675771,0.002600832,0.920419],"study_design_scores_gemma":[0.001365768,0.001828358,1.704206e-7,0.000524219,0.0001288978,0.00005314227,0.00005552807,0.0002100876,0.0148689,0.000003059578,0.9801041,0.0008577446],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003928356,0.9891362,0.0006509371,0.00005154718,0.0008677832,0.004448138,0.0008067916,0.0000500129,0.00006022672],"genre_scores_gemma":[0.0001851058,0.9908943,0.0001958396,0.0002776714,0.001564465,0.003525586,0.0005672877,0.0004634316,0.002326327],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9775033,"threshold_uncertainty_score":0.99953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04591931529685724,"score_gpt":0.368575812813233,"score_spread":0.3226564975163758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}