{"id":"W1987440530","doi":"10.1016/j.gde.2014.03.006","title":"The emerging role of exosomes in Wnt secretion and transport","year":2014,"lang":"en","type":"review","venue":"Current Opinion in Genetics & Development","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Microvesicles; Biology; Wnt signaling pathway; Cell biology; Secretion; Morphogen; Cell signaling; Endosome; Signal transduction; microRNA; Intracellular; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110919,0.0007265024,0.001407352,0.001124947,0.0003048538,0.00219008,0.0007716384,0.002170481,0.001608859],"category_scores_gemma":[0.0007725842,0.0002744722,0.000514276,0.001256075,0.001224792,0.002992534,0.001726364,0.002622727,0.0008138834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007173927,"about_ca_system_score_gemma":0.00106837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004681576,"about_ca_topic_score_gemma":0.0006923922,"domain_scores_codex":[0.9997379,0.00004581631,0.0000313809,0.00005168637,0.00009525254,0.0000379538],"domain_scores_gemma":[0.9996181,0.0001741012,0.00004917441,0.0000152279,0.00008949004,0.00005394344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001821127,0.00005537073,0.0005785245,0.008806202,0.000131309,0.0008338796,0.0001625696,0.0008276022,0.016973,0.02468131,0.0241721,0.9225961],"study_design_scores_gemma":[0.00002890817,0.00007160281,0.001110221,0.001731599,0.0001096537,0.001881926,0.000183511,0.0003823813,0.003486346,0.008895241,0.9820764,0.00004221416],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004817251,0.9961499,0.0009097148,0.001050732,0.00055687,0.000004532878,0.00002948412,0.00001283059,0.0008042347],"genre_scores_gemma":[0.002566828,0.9953377,0.000576683,0.0003782946,0.0004265713,0.000007329006,0.00004329431,0.000002401731,0.0006609168],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00219008,"threshold_uncertainty_score":0.005866051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02727953447741293,"score_gpt":0.3363471921439198,"score_spread":0.3090676576665069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}