{"id":"W1987464084","doi":"10.1371/journal.pone.0050730","title":"Sonoporation Delivery of Monoclonal Antibodies against Human Papillomavirus 16 E6 Restores p53 Expression in Transformed Cervical Keratinocytes","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lakehead University; Thunder Bay Regional Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Sonoporation; Transfection; Monoclonal antibody; Microbubbles; Antibody; Cancer research; Cell culture; In vivo; Biology; Medicine; Molecular biology; Immunology; Ultrasound","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001151272,0.0001764239,0.0002018459,0.0002095412,0.0001109756,0.0002084625,0.0001836623,0.0002300375,0.0007959403],"category_scores_gemma":[0.0001145751,0.0001359567,0.0001524143,0.0001006904,0.0001996124,0.000154957,0.0001638809,0.0003568571,0.0001970871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001927175,"about_ca_system_score_gemma":0.0001642572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009620521,"about_ca_topic_score_gemma":0.001000133,"domain_scores_codex":[0.9999174,0.00001260782,0.000008384221,0.00001461055,0.00002740345,0.00001959999],"domain_scores_gemma":[0.9999263,0.00002047836,0.00001677866,0.00001360314,0.000009181733,0.00001364581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004225658,0.00001348282,0.00002395642,0.00001491915,0.000001419467,0.00002334207,0.00001397432,0.00004207089,0.9989213,0.0000505529,0.00001195698,0.0008407881],"study_design_scores_gemma":[0.000004583575,0.00009242574,0.0004355668,0.000001824044,0.000003220829,0.00004805417,0.00001203461,0.0003392578,0.9983595,0.00001376801,0.0006885099,0.00000118095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956732,0.0004631732,0.002461342,0.00005421156,0.00001623474,0.0000181605,0.00006645788,0.00009319175,0.001153989],"genre_scores_gemma":[0.9926978,0.0008188217,0.003049167,0.00002432367,0.000003904117,0.00002575676,0.000103887,0.00002801961,0.003248351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009620521,"threshold_uncertainty_score":0.002662659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1071509893192701,"score_gpt":0.3268237351921545,"score_spread":0.2196727458728844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}