{"id":"W1987507910","doi":"10.1021/bi036018e","title":"Dynamic Relationships among Type IIa Bacteriocins:  Temperature Effects on Antimicrobial Activity and on Structure of the C-Terminal Amphipathic α Helix as a Receptor-Binding Region","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Helix (gastropod); Amphiphile; Terminal (telecommunication); Antimicrobial; Chemistry; Bacteriocin; Amino terminal; Receptor; Biophysics; Biochemistry; Stereochemistry; Peptide sequence; Biology; Ecology; Copolymer; Gene; Organic chemistry; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207288,0.0001887562,0.0001447416,0.0001141825,0.0001128759,0.0002336238,0.0001382066,0.0001713502,0.000461117],"category_scores_gemma":[0.0003326249,0.0001020358,0.0001296287,0.0001442179,0.0001726306,0.0002536309,0.00008746512,0.000214652,0.00006716439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002401155,"about_ca_system_score_gemma":0.0001465824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007070643,"about_ca_topic_score_gemma":0.0005016018,"domain_scores_codex":[0.9999355,0.00001026938,0.000003997308,0.00001792098,0.00001783602,0.00001434308],"domain_scores_gemma":[0.9998744,0.00004200153,0.00004037827,0.00000635853,0.00001663443,0.00002020133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003049214,0.00005482237,0.003492393,0.00005103895,0.00001856959,0.00007879168,0.00003474621,0.007584676,0.9863749,0.0001613589,0.00002379365,0.00182011],"study_design_scores_gemma":[0.00005387556,0.000662146,0.02838394,0.00001430249,0.00005465398,0.000264629,0.0001078237,0.1038897,0.8654848,0.000278299,0.0007736481,0.00003204796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990846,0.0001725745,0.0004521278,0.000008942758,9.913462e-7,0.000003734016,0.00004970921,0.000007197847,0.000220154],"genre_scores_gemma":[0.9991441,0.0001342632,0.0005480961,0.000005316095,6.499413e-7,0.00000536283,0.00009673457,0.000004243448,0.00006118785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007070643,"threshold_uncertainty_score":0.001742184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008850811276991635,"score_gpt":0.2026215771362243,"score_spread":0.1937707658592327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}