{"id":"W1987507910","doi":"10.1021/bi036018e","title":"Dynamic Relationships among Type IIa Bacteriocins:  Temperature Effects on Antimicrobial Activity and on Structure of the C-Terminal Amphipathic α Helix as a Receptor-Binding Region","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Helix (gastropod); Amphiphile; Terminal (telecommunication); Antimicrobial; Chemistry; Bacteriocin; Amino terminal; Receptor; Biophysics; Biochemistry; Stereochemistry; Peptide sequence; Biology; Ecology; Copolymer; Gene; Organic chemistry; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005428828,0.0001366434,0.0001140291,0.00000732529,0.0002458814,0.00003690908,0.0001375026,0.0002705562,0.000007895223],"category_scores_gemma":[0.00008257742,0.00005387309,0.00005226173,0.000181791,0.00009020786,0.00003491687,0.00005199412,0.0003559748,0.000002627472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005735978,"about_ca_system_score_gemma":0.0000186557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002052577,"about_ca_topic_score_gemma":0.00002214802,"domain_scores_codex":[0.9993723,0.00004674372,0.00009298452,0.0002438094,0.0001069342,0.0001372162],"domain_scores_gemma":[0.9996833,0.00004842848,0.0001052703,0.00008750354,0.00002719064,0.00004834617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007509057,0.00003805651,0.002346665,0.00003968937,0.000008310348,0.000002860208,0.00003324232,0.000002546729,0.9966902,0.00001216894,0.00002495272,0.000726254],"study_design_scores_gemma":[0.0001504611,0.0002050311,0.1512536,0.0003973302,0.00001024736,0.00002057583,0.00001964066,0.000002609225,0.8477648,0.00005446581,0.00001329579,0.0001079893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991292,0.0000233608,7.482896e-8,0.0004711499,0.0001368436,0.0001383989,0.00004383169,0.00001619103,0.00004090721],"genre_scores_gemma":[0.9996845,0.00002152598,0.00001318006,0.00005933848,0.00007389834,0.000001028797,0.00004773336,0.00000151604,0.00009727196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1489254,"threshold_uncertainty_score":0.2196881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008850811276991635,"score_gpt":0.2026215771362243,"score_spread":0.1937707658592327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}