{"id":"W1987530975","doi":"10.1016/j.cyto.2008.07.370","title":"288 Chimeric fusokines borne of the marriage of the TGFβ receptor II ectodomain and pro-inflammatory cytokines IL2 and GMCSF for breast cancer immunotherapy","year":2008,"lang":"en","type":"article","venue":"Cytokine","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Ectodomain; Medicine; Immunotherapy; Cancer research; Cancer immunotherapy; Immunology; Transforming growth factor; Cancer; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001094134,0.0003085228,0.000163227,0.0001793004,0.00012978,0.0002569917,0.0001581146,0.0003105536,0.002309607],"category_scores_gemma":[0.00009115402,0.00009980137,0.0002034759,0.0001459498,0.0001561779,0.0001444287,0.000190579,0.0005084692,0.0005311128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002133002,"about_ca_system_score_gemma":0.0001280321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002384755,"about_ca_topic_score_gemma":0.0002821269,"domain_scores_codex":[0.9999262,0.00001326018,0.00000427123,0.000009702023,0.00002460029,0.00002192103],"domain_scores_gemma":[0.9999582,0.00001032402,0.00001007236,0.000006180001,0.000005646587,0.000009775287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002418177,0.00002678625,0.0001175605,0.00001601198,0.000004425933,0.00007789041,0.00001063601,0.0002199307,0.9968296,0.0004276656,0.00008245349,0.001945175],"study_design_scores_gemma":[0.00007711989,0.0003989419,0.0007932806,0.000006170959,0.00002289518,0.000401755,0.0000289449,0.001238808,0.9885766,0.0001504162,0.008299251,0.000005870254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849518,0.002203722,0.009115883,0.0001519572,0.0001372202,0.00005982465,0.0004228656,0.0000693433,0.002887412],"genre_scores_gemma":[0.9903018,0.0008252958,0.004455172,0.00005071606,0.00001932781,0.0000349506,0.0005166803,0.00001878595,0.003777255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002309607,"threshold_uncertainty_score":0.007726431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005073865303415496,"score_gpt":0.214059239938403,"score_spread":0.2089853746349875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}