{"id":"W1987566523","doi":"10.1371/journal.pone.0024003","title":"Fluoxetine during Development Reverses the Effects of Prenatal Stress on Depressive-Like Behavior and Hippocampal Neurogenesis in Adolescence","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Maternal Mental Health During Pregnancy and Postpartum","field":"Medicine","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fluoxetine; Offspring; Neurogenesis; Hippocampal formation; Prenatal stress; Serotonin reuptake inhibitor; Behavioural despair test; Psychology; Open field; Endocrinology; Hippocampus; Internal medicine; Medicine; Pregnancy; Psychiatry; Serotonin; Antidepressant; Neuroscience; Biology; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005673182,0.0001139479,0.0002005832,0.00005672176,0.00005556835,0.000003147317,0.00007820813,0.00003954135,0.0000187455],"category_scores_gemma":[0.00004758863,0.00008329209,0.0000166895,0.00005448853,0.00005012097,0.00003537478,0.00006808903,0.0001383656,0.000004860738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002544276,"about_ca_system_score_gemma":0.00002773536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004456271,"about_ca_topic_score_gemma":0.00001392151,"domain_scores_codex":[0.9991328,0.00005356802,0.0002180506,0.0001836349,0.0002237944,0.0001881167],"domain_scores_gemma":[0.9995645,0.00006178043,0.00008150939,0.0001810906,0.00002240971,0.00008874399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007791279,0.001924628,0.967454,0.01942256,0.00003306703,0.0002260807,0.001213565,9.605903e-8,0.008296181,0.000004634623,3.326775e-7,0.000645741],"study_design_scores_gemma":[0.0005309543,0.0001489436,0.5071416,0.01555942,0.00004508747,0.000008127014,0.00001139603,9.966868e-7,0.4765137,7.468177e-7,2.193273e-7,0.00003871458],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998455,0.0006614648,2.589755e-7,0.00002515739,0.00006253456,0.0007211515,0.000005485201,0.00001751859,0.00005146072],"genre_scores_gemma":[0.9991405,0.0002234501,0.000274151,0.00007817797,0.00002077132,0.0001253072,0.000002615049,0.00001315836,0.0001218849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4682176,"threshold_uncertainty_score":0.3396553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03411307052037765,"score_gpt":0.2395564638458096,"score_spread":0.2054433933254319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}