{"id":"W1987584130","doi":"10.1074/jbc.m111.294561","title":"Biochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent l-Serine Dehydrogenase","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Basic Energy Sciences; Biological and Environmental Research; RIKEN; Office of Science; National Institutes of Health; Government of Canada; Genome Canada; Ontario Genomics; National Institute of General Medical Sciences; Ontario Genomics Institute; U.S. Department of Energy","keywords":"NAD+ kinase; Dehydrogenase; Cofactor; Biochemistry; Enzyme; Active site; Stereochemistry; Serine; Chemistry; Oxidoreductase; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002948208,0.0001954139,0.0005254067,0.00002001547,0.00004944135,0.00001316357,0.0002181125,0.000195403,0.0006359552],"category_scores_gemma":[0.0003560729,0.0001179145,0.000111913,0.00005917513,0.0003074611,0.000093593,0.0001000654,0.0002312816,0.000002068385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003444179,"about_ca_system_score_gemma":0.00003171564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001471931,"about_ca_topic_score_gemma":5.772912e-7,"domain_scores_codex":[0.9986441,0.00006265783,0.0006506634,0.0002369547,0.000212251,0.0001934451],"domain_scores_gemma":[0.9988157,0.00007001015,0.0006244478,0.0001591555,0.0001939631,0.0001367011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007086386,0.00003226132,0.0024928,0.00005868451,0.00005831863,0.00005099457,0.0001287263,1.896473e-7,0.9962743,0.00000697001,0.0000296393,0.0001584954],"study_design_scores_gemma":[0.0007687315,0.0002100462,0.006694708,0.00007387621,0.0000394285,0.0001786442,0.000171194,0.000001578818,0.9898655,0.001829409,0.00002771191,0.0001391994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981449,0.001407284,0.00002421619,0.00004265476,0.0001553129,0.00008558528,0.00005229609,0.00001530479,0.0000724476],"genre_scores_gemma":[0.9964065,0.0001211147,0.003104196,0.00003309533,0.0002917119,0.000003743118,0.000008283616,0.000006474537,0.00002487802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006408809,"threshold_uncertainty_score":0.6963264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0402499406315977,"score_gpt":0.2557188781162589,"score_spread":0.2154689374846612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}