{"id":"W1987588985","doi":"10.1002/cbic.201200526","title":"Sequence‐Dependent Structural Dynamics of Primate Adenosine‐to‐Inosine Editing Substrates","year":2012,"lang":"en","type":"article","venue":"ChemBioChem","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Inosine; ADAR; Oligonucleotide; Adenosine; Adenosine deaminase; Biology; RNA editing; Nucleotide; Sequence (biology); Biophysics; RNA; Chemistry; Stereochemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736337,0.0001875482,0.0001917435,0.0001230843,0.0002362506,0.0005030672,0.0002485631,0.0002862299,0.0009185174],"category_scores_gemma":[0.0005446767,0.0001890922,0.0001768783,0.0001239649,0.0001891349,0.0002720638,0.0001076106,0.0004224019,0.000387603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003313421,"about_ca_system_score_gemma":0.0001325189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001013173,"about_ca_topic_score_gemma":0.001357793,"domain_scores_codex":[0.9999167,0.0000138855,0.000004052072,0.00002879553,0.0000189691,0.00001760895],"domain_scores_gemma":[0.9997808,0.00006078636,0.00006425599,0.00001689076,0.0000313122,0.00004593132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001318694,0.00001710257,0.002052877,0.00003272668,0.0000181997,0.0001487789,0.0002005406,0.001427701,0.9936746,0.0003722598,0.00007329153,0.001850075],"study_design_scores_gemma":[0.00001469505,0.0004012002,0.04398789,0.00002397109,0.00005109732,0.0008943991,0.0002764024,0.03102145,0.9188007,0.0007308099,0.003724633,0.00007270363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978493,0.0002205577,0.001066352,0.00002198453,0.000002757342,0.000003307763,0.0000884246,0.00003090506,0.0007162939],"genre_scores_gemma":[0.9982126,0.0001360037,0.0009801121,0.00001683834,0.000002262223,0.000007122722,0.0002671554,0.00003231404,0.0003455073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001013173,"threshold_uncertainty_score":0.003072739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01455139570857964,"score_gpt":0.2804954873321559,"score_spread":0.2659440916235762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}