{"id":"W1987605547","doi":"10.1016/j.bpj.2009.12.717","title":"Oligomeric Size and Configuration of the M2 Muscarinic and β2 Adrenergic Receptors in Live Cells as Determined by Pixel-Level FRET","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Tetramer; Chemistry; Crystallography; Biophysics; Fluorescence; Physics; Optics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003942679,0.0002101296,0.0004079945,0.0001891981,0.0004690442,0.0009757701,0.0004165086,0.0006531118,0.001566795],"category_scores_gemma":[0.0003759006,0.0002866608,0.0002407572,0.0002135741,0.0004449789,0.0008489839,0.0003265812,0.001208326,0.0005962399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005775853,"about_ca_system_score_gemma":0.000215176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006441772,"about_ca_topic_score_gemma":0.0007835806,"domain_scores_codex":[0.9998155,0.00002116773,0.00001353823,0.00006863836,0.00004646054,0.00003463002],"domain_scores_gemma":[0.9998379,0.00005226865,0.00002495086,0.00002899132,0.00002373688,0.00003223835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008451215,0.00002344263,0.0002400235,0.00001653573,0.000006830267,0.00002687462,0.00007631637,0.0001001524,0.9979614,0.0005112795,0.00008836287,0.000864403],"study_design_scores_gemma":[0.0000213289,0.00008214181,0.007447765,0.000008689404,0.00001976597,0.0002869249,0.0002053378,0.006105416,0.9834511,0.0004402673,0.001911243,0.0000199251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861417,0.0006357377,0.009946147,0.0002029221,0.00002511295,0.0000130716,0.0004462444,0.00008713864,0.002501855],"genre_scores_gemma":[0.9871218,0.0006907277,0.008713574,0.0002111031,0.00001490096,0.00006496523,0.0008778448,0.00009495418,0.00221021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001566795,"threshold_uncertainty_score":0.005241454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006256886666181937,"score_gpt":0.2186828996780047,"score_spread":0.2124260130118227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}