{"id":"W1987622504","doi":"10.1016/j.lungcan.2011.05.027","title":"ALK fusion gene positive lung cancer and 3 cases treated with an inhibitor for ALK kinase activity","year":2011,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Toronto General Hospital","funders":"Pfizer","keywords":"Crizotinib; Medicine; Anaplastic lymphoma kinase; ALK inhibitor; Lung cancer; Internal medicine; Oncology; Chemotherapy; Fluorescence in situ hybridization; Adenocarcinoma; Tyrosine-kinase inhibitor; Fusion gene; Cancer; Cancer research; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003296049,0.001318633,0.001403357,0.002465457,0.002999589,0.0008495059,0.001486003,0.005176051,0.005217499],"category_scores_gemma":[0.001757533,0.001032222,0.002991277,0.001075314,0.001869029,0.0006799058,0.001115083,0.002158599,0.001123856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001943831,"about_ca_system_score_gemma":0.001057305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005847335,"about_ca_topic_score_gemma":0.00798942,"domain_scores_codex":[0.999198,0.00004866952,0.00007244563,0.0001636795,0.000138271,0.0003788787],"domain_scores_gemma":[0.9990539,0.0002573456,0.0001732832,0.00006555398,0.00005998614,0.0003898416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0005963384,0.0003320864,0.03656957,0.0000498726,0.0000551082,0.9572011,0.0001665678,0.0001755124,0.00151968,0.0001421948,0.0003800932,0.002811872],"study_design_scores_gemma":[0.0001461269,0.001094899,0.0875783,0.00001737856,0.0001526924,0.9048995,0.0003822741,0.0004819482,0.002777561,0.0002687474,0.00215466,0.00004581645],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9716669,0.00419944,0.001479939,0.003290137,0.0005240846,0.0002873221,0.0006728523,0.0001071455,0.01777202],"genre_scores_gemma":[0.9916325,0.00102297,0.0006383568,0.001242098,0.0007559944,0.00006324592,0.0004125488,0.0000390409,0.004193293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005847335,"threshold_uncertainty_score":0.01745427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02078302751036611,"score_gpt":0.3394637568106692,"score_spread":0.3186807293003031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}