{"id":"W1987650885","doi":"10.1128/jcm.00634-10","title":"High-Throughput Genotyping of Single Nucleotide Polymorphisms in the <i>Plasmodium falciparum dhfr</i> Gene by Asymmetric PCR and Melt-Curve Analysis","year":2010,"lang":"en","type":"article","venue":"Journal of Clinical Microbiology","topic":"Malaria Research and Control","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Provincial Laboratory of Public Health; University of Alberta","funders":"","keywords":"Biology; TaqMan; Genotyping; Melting curve analysis; Single-nucleotide polymorphism; High Resolution Melt; SNP genotyping; Amplicon; Molecular biology; Plasmodium falciparum; Genotype; Variants of PCR; Genetics; Molecular Inversion Probe; Polymerase chain reaction; Gene; Virology; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002626918,0.0009034911,0.001306982,0.001630614,0.0003632311,0.001012409,0.001043529,0.0008837197,0.0008763378],"category_scores_gemma":[0.004132671,0.0005656074,0.0009855866,0.001001407,0.0004171634,0.0006752376,0.0007338599,0.0009812813,0.001021383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005623713,"about_ca_system_score_gemma":0.0003380321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008610274,"about_ca_topic_score_gemma":0.001559098,"domain_scores_codex":[0.9946324,0.001638464,0.0003059032,0.001176296,0.001977571,0.0002693473],"domain_scores_gemma":[0.9978852,0.0008442422,0.0003733127,0.0002503711,0.0005645744,0.00008239342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001510122,0.0001350953,0.002545716,0.0001005223,0.00004565681,0.00005146033,0.00007611932,0.001250434,0.9753562,0.0002515871,0.0003239342,0.01971224],"study_design_scores_gemma":[0.00005360054,0.000525228,0.01930359,0.00002641073,0.0001025681,0.0004669737,0.00003882901,0.05572953,0.9195373,0.0003795481,0.003740274,0.0000960329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3765804,0.001362504,0.6127029,0.0002271141,0.0001118521,0.0009972325,0.002863858,0.003008075,0.002146082],"genre_scores_gemma":[0.4415009,0.001125513,0.5485363,0.0001945397,0.000120219,0.001572242,0.004362567,0.0003097216,0.002278033],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002626918,"threshold_uncertainty_score":0.01389265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02959129162538359,"score_gpt":0.3282292523359914,"score_spread":0.2986379607106078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}