{"id":"W1987825638","doi":"10.2337/db11-1314","title":"Transgenerational Glucose Intolerance With <i>Igf2</i>/<i>H19</i> Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia","year":2012,"lang":"en","type":"article","venue":"Diabetes","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":310,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Offspring; Impaired glucose tolerance; Gestational diabetes; Genomic imprinting; Endocrinology; Epigenetics; Internal medicine; Biology; Islet; Diabetes mellitus; DNA methylation; Pregnancy; Gestation; Type 2 diabetes; Gene; Medicine; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001793314,0.0004155966,0.0002387105,0.0005196252,0.0001810195,0.0002277267,0.0002977233,0.000308603,0.001601676],"category_scores_gemma":[0.00009598683,0.0002407156,0.0004597282,0.0002366355,0.0003166134,0.0001717292,0.0003108262,0.0008677247,0.000244209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002337143,"about_ca_system_score_gemma":0.0001692616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006869418,"about_ca_topic_score_gemma":0.0013145,"domain_scores_codex":[0.9997565,0.00002192871,0.00002858357,0.00008816107,0.00004793152,0.00005689664],"domain_scores_gemma":[0.9997975,0.00001737285,0.00007467284,0.00003163264,0.0000114518,0.00006734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001432085,0.00003394309,0.000843386,0.00001757696,0.000008092973,0.00009259321,0.00002802404,0.00002454253,0.997763,0.0001046043,0.00002636599,0.0009146361],"study_design_scores_gemma":[0.00004803954,0.0007110389,0.03365505,0.00001464414,0.00005979217,0.0007139332,0.00008720417,0.0005968874,0.960929,0.0001004318,0.003069804,0.00001410238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942456,0.0005865908,0.003355594,0.0000729683,0.00005034287,0.00003077139,0.0006219453,0.0001209303,0.00091519],"genre_scores_gemma":[0.9890206,0.0008354404,0.003576076,0.0001388265,0.00002206407,0.0001207116,0.001165815,0.00009718021,0.005023214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001601676,"threshold_uncertainty_score":0.0053581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007940225014701258,"score_gpt":0.2156889418735279,"score_spread":0.2077487168588266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}