{"id":"W1987825638","doi":"10.2337/db11-1314","title":"Transgenerational Glucose Intolerance With <i>Igf2</i>/<i>H19</i> Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia","year":2012,"lang":"en","type":"article","venue":"Diabetes","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":310,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Offspring; Impaired glucose tolerance; Gestational diabetes; Genomic imprinting; Endocrinology; Epigenetics; Internal medicine; Biology; Islet; Diabetes mellitus; DNA methylation; Pregnancy; Gestation; Type 2 diabetes; Gene; Medicine; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001333315,0.0002057654,0.0001751058,0.00004546094,0.00007367251,0.00003926953,0.0001486932,0.000112083,0.00003604509],"category_scores_gemma":[0.00002184011,0.0001913993,0.00004457105,0.0001226737,0.00004819925,0.00001471679,0.00004289228,0.0001069365,0.00001105051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001413119,"about_ca_system_score_gemma":0.00003982131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002114439,"about_ca_topic_score_gemma":0.00002536001,"domain_scores_codex":[0.9987925,0.00005418403,0.000257994,0.0002994429,0.0001323737,0.0004635645],"domain_scores_gemma":[0.9994956,0.00001126426,0.00005833095,0.0002677085,0.00004657567,0.000120499],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006754864,0.0001211403,0.02831767,0.00001399507,0.00002705273,1.482345e-7,0.0001042495,0.0001426523,0.9679331,0.00002819138,0.0002481566,0.003056836],"study_design_scores_gemma":[0.0007320558,0.0002141086,0.01227953,0.00001511771,0.000009650515,0.00000404061,0.00002836104,0.0002116438,0.9790294,0.00001076257,0.007183463,0.0002818242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969648,0.001440516,0.00081671,0.0001894841,0.0001320101,0.0001933283,0.00003782567,0.00001337551,0.0002120189],"genre_scores_gemma":[0.9963138,0.0001609781,0.002107186,0.0006030263,0.0002425805,0.00009888781,0.0002876294,0.00003428781,0.000151617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01603815,"threshold_uncertainty_score":0.7805037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007940225014701258,"score_gpt":0.2156889418735279,"score_spread":0.2077487168588266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}