{"id":"W1987870207","doi":"10.1089/dna.2011.1268","title":"Enhancer-Blocking Activity Is Associated with Hypersensitive Site V Sequences in the Human Growth Hormone Locus Control Region","year":2011,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Enhancer; CTCF; Biology; Locus control region; Molecular biology; Enhancer RNAs; Locus (genetics); Transcription factor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001362889,0.0002681204,0.0001704256,0.0001611458,0.00009445,0.0001677503,0.0001207658,0.0001788338,0.00146147],"category_scores_gemma":[0.0001932086,0.0001819225,0.0002476715,0.00008107634,0.0002028974,0.00006364127,0.0001563293,0.0004417573,0.0003348406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002651767,"about_ca_system_score_gemma":0.0002095276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007449932,"about_ca_topic_score_gemma":0.001229124,"domain_scores_codex":[0.9997951,0.00003212152,0.00001349156,0.00005509998,0.00006180376,0.00004228096],"domain_scores_gemma":[0.9997875,0.00006584902,0.00006849311,0.00002580692,0.000009997773,0.00004233172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002677063,0.000007970565,0.000164867,0.000006877154,0.000001822518,0.00001717752,0.00000480121,0.000009747012,0.9993962,0.00002275973,0.000005750303,0.0003353235],"study_design_scores_gemma":[0.00001372091,0.0003286458,0.01606869,0.000005972514,0.0000115129,0.0004345925,0.0000120284,0.0004472837,0.9814205,0.00003366667,0.001220166,0.0000033138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968956,0.0006807172,0.001648001,0.00002399449,0.00000841353,0.00001261752,0.000104088,0.00004867699,0.0005779051],"genre_scores_gemma":[0.9961826,0.0002315613,0.00160606,0.00002673557,0.000005460543,0.0000176,0.0006315924,0.00001771465,0.001280663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00146147,"threshold_uncertainty_score":0.004889131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007793182229124,"score_gpt":0.2000492139662536,"score_spread":0.1899712821439624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}