{"id":"W1987889725","doi":"10.1139/o05-165","title":"Secretion of human glucocerebrosidase from stable transformed insect cells using native signal sequences","year":2006,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glucocerebrosidase; Insect; Secretion; Biology; SIGNAL (programming language); Cell biology; Biochemistry; Chemistry; Botany; Enzyme; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003373679,0.0005252055,0.0004256017,0.0001942654,0.0001892765,0.0005395465,0.0003926308,0.0003245438,0.001124037],"category_scores_gemma":[0.0001751692,0.0002199358,0.0003955816,0.0005441383,0.0002818384,0.0002453002,0.0003163163,0.0007337337,0.0009829258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005303288,"about_ca_system_score_gemma":0.0002555575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001523494,"about_ca_topic_score_gemma":0.001412897,"domain_scores_codex":[0.9996883,0.00005094151,0.00006192919,0.00007488103,0.00007967723,0.00004418617],"domain_scores_gemma":[0.999894,0.00001982349,0.000025134,0.00002434636,0.0000179436,0.00001861923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009780387,0.00002728392,0.0001261916,0.00006914688,0.00001182545,0.0000768088,0.00004240834,0.00006477598,0.9979912,0.0001156265,0.00008191317,0.001295031],"study_design_scores_gemma":[0.00005789319,0.0003492985,0.001916499,0.0000156171,0.00004223347,0.0002913239,0.00004052561,0.001550977,0.986164,0.00006228407,0.009496136,0.00001332649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9611558,0.004346868,0.02321056,0.0002768594,0.0003040665,0.0003282686,0.00394389,0.0004875582,0.005946201],"genre_scores_gemma":[0.9462667,0.003141483,0.02687879,0.00013349,0.00005745437,0.0001719319,0.01316316,0.0001639851,0.01002302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001523494,"threshold_uncertainty_score":0.003847837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122108316566965,"score_gpt":0.2450628930030408,"score_spread":0.2338418098373712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}