{"id":"W1987953948","doi":"10.1159/000065588","title":"The Clinical Importance of Proton Pump Inhibitor Pharmacokinetics","year":2002,"lang":"en","type":"review","venue":"Digestion","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; University of Alberta","funders":"","keywords":"Lansoprazole; Pantoprazole; Proton-pump inhibitor; Omeprazole; Dosing; Pharmacokinetics; Bioavailability; Pharmacodynamics; Pharmacology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002818426,0.0002371019,0.0009272868,0.00004616861,0.0000515336,0.00001088549,0.00009660052,0.0002084957,0.00003318563],"category_scores_gemma":[0.0002272565,0.0001283907,0.0004344723,0.0001464732,0.00009681312,0.00002392286,0.00002980656,0.0003820554,0.0000903959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006688671,"about_ca_system_score_gemma":0.000107574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.569059e-7,"about_ca_topic_score_gemma":1.806876e-7,"domain_scores_codex":[0.9982972,0.000114899,0.00085925,0.0002561287,0.0002796059,0.0001928998],"domain_scores_gemma":[0.9987219,0.0001773228,0.0005407284,0.0003622144,0.00008807756,0.0001097604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001429773,0.0002637141,0.009353064,0.004016972,0.0001796784,0.000105136,0.000003976794,4.551917e-8,1.416574e-7,0.0000227773,0.000327542,0.9857126],"study_design_scores_gemma":[0.0007054915,0.0004655496,0.001906792,0.004442195,0.001673987,0.00006092713,6.202868e-7,0.000004095301,0.00001580646,0.00001244218,0.9906489,0.0000631675],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009871894,0.9952641,0.000002984518,0.00003109377,0.0003602863,0.002470258,0.00002245921,0.00003036606,0.0008313056],"genre_scores_gemma":[0.002404606,0.9954071,0.00006209491,0.00001614123,0.0004368835,0.0002492278,0.0001390383,0.00003493492,0.001249955],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9903214,"threshold_uncertainty_score":0.5235619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1051329362723938,"score_gpt":0.4320649104071457,"score_spread":0.3269319741347519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}