{"id":"W1987958896","doi":"10.1002/bip.22595","title":"<scp>DNA</scp>mechatronic devices switched by<scp>K</scp><sup>+</sup>and by<scp>S</scp>r<sup>2+</sup>are structurally, topologically, and electronically distinct","year":2014,"lang":"en","type":"article","venue":"Biopolymers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Conformational isomerism; Circular dichroism; G-quadruplex; DNA; Duplex (building); Molecular switch; Guanine; Crystallography; Stereochemistry; Chromophore; Topology (electrical circuits); Nucleotide; Molecule; Photochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009005709,0.000229596,0.0001317783,0.0001000497,0.0002250968,0.0003986139,0.0003474773,0.0003337602,0.002346796],"category_scores_gemma":[0.00031277,0.0001122,0.0001146064,0.0001394027,0.0005654487,0.0003965818,0.000239518,0.0003847574,0.0004459126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002677857,"about_ca_system_score_gemma":0.0001697913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002530521,"about_ca_topic_score_gemma":0.0003416935,"domain_scores_codex":[0.9998491,0.00001144429,0.00001077099,0.00005873902,0.00005448966,0.00001556788],"domain_scores_gemma":[0.9998393,0.00003771999,0.00004429783,0.00003331337,0.00002747007,0.00001791792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007795605,0.00001536445,0.0003736746,0.00006581671,0.00000619917,0.00008828617,0.00004611275,0.0004867686,0.987718,0.002056358,0.000242157,0.008823299],"study_design_scores_gemma":[0.000005382604,0.0001084369,0.001142582,0.000002820246,0.000004183433,0.0001704565,0.00002984528,0.00136599,0.9916828,0.0002963442,0.005184074,0.000007167342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738896,0.0004077618,0.01412945,0.0002046718,0.00005578296,0.00003987545,0.0004183538,0.0003858944,0.01046854],"genre_scores_gemma":[0.9897713,0.0001452159,0.005775382,0.0000801486,0.000006688251,0.00004676168,0.000299987,0.00004407726,0.003830313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002346796,"threshold_uncertainty_score":0.007850766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005269217945655958,"score_gpt":0.2308569864162908,"score_spread":0.2255877684706348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}