{"id":"W1987958896","doi":"10.1002/bip.22595","title":"<scp>DNA</scp>mechatronic devices switched by<scp>K</scp><sup>+</sup>and by<scp>S</scp>r<sup>2+</sup>are structurally, topologically, and electronically distinct","year":2014,"lang":"en","type":"article","venue":"Biopolymers","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Conformational isomerism; Circular dichroism; G-quadruplex; DNA; Duplex (building); Molecular switch; Guanine; Crystallography; Stereochemistry; Chromophore; Topology (electrical circuits); Nucleotide; Molecule; Photochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006117855,0.001145487,0.001090402,0.0001878794,0.0005867775,0.0002993294,0.0008695991,0.001136302,0.000006616852],"category_scores_gemma":[0.001557188,0.0009500511,0.0004204347,0.0004240632,0.001057292,0.00005109784,0.0006399748,0.0006570496,0.0000118857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001013732,"about_ca_system_score_gemma":0.0001412252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001160139,"about_ca_topic_score_gemma":0.000104439,"domain_scores_codex":[0.9943428,0.0003826676,0.0009241923,0.00202311,0.0006006481,0.001726584],"domain_scores_gemma":[0.9968586,0.000576226,0.0006429256,0.00103489,0.0002206894,0.000666681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004715731,0.0002538355,0.01056927,0.0001662449,0.000800345,0.0000217516,0.0002765317,0.00002481187,0.9478163,0.0004061668,0.02997733,0.009640307],"study_design_scores_gemma":[0.00158898,0.001628796,0.001248415,0.00008950947,0.0004516123,0.0001545586,0.002917292,0.001199175,0.7971117,0.0006718559,0.1924949,0.0004431768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849966,0.01086067,0.001406111,0.0004035032,0.00007439125,0.0005069104,0.0002369586,0.0003076335,0.001207275],"genre_scores_gemma":[0.990266,0.0024557,0.001609071,0.001265328,0.0004060038,0.00004477278,0.0007919004,0.0001285278,0.003032732],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1625175,"threshold_uncertainty_score":0.999295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005269217945655958,"score_gpt":0.2308569864162908,"score_spread":0.2255877684706348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}