{"id":"W1987968608","doi":"10.1534/g3.111.000430","title":"A Synthetic Human Kinase Can Control Cell Cycle Progression in Budding Yeast","year":2011,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Yeast; Biology; Saccharomyces cerevisiae; Cell cycle; Kinase; Cell biology; Biochemistry; Genetics; Computational biology; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001887355,0.000555518,0.0002351064,0.0002353669,0.0001892141,0.0004107994,0.0002719406,0.0002198563,0.001121896],"category_scores_gemma":[0.000159498,0.000198399,0.0002318336,0.0002228573,0.000215349,0.0001712621,0.0002763525,0.0003530448,0.0005773374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005504715,"about_ca_system_score_gemma":0.0002388355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005328013,"about_ca_topic_score_gemma":0.0008947793,"domain_scores_codex":[0.9998286,0.00003088198,0.00002646574,0.00004533305,0.00004422159,0.00002453019],"domain_scores_gemma":[0.999887,0.00002315715,0.00002261181,0.00002619064,0.00001176865,0.00002922981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001613191,0.0000240113,0.0001071362,0.00004929944,0.000004456516,0.00002814859,0.00001103006,0.0001580585,0.9976681,0.0002015446,0.00005164694,0.001535309],"study_design_scores_gemma":[0.00002032249,0.0001436738,0.0007679245,0.000007345214,0.00001074962,0.0001591177,0.00001366062,0.001068283,0.9899771,0.00008248816,0.007743196,0.000006187379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791285,0.005419279,0.009583825,0.0001607298,0.0001989287,0.0001192908,0.001561819,0.0002908377,0.003536846],"genre_scores_gemma":[0.9799244,0.002136995,0.009586321,0.0000548008,0.00001765056,0.00008202415,0.002436881,0.00009499762,0.005665909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001121896,"threshold_uncertainty_score":0.003994048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922800853259292,"score_gpt":0.2719484082962965,"score_spread":0.2527203997637036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}