{"id":"W1987973699","doi":"10.1002/ibd.21127","title":"Efficacy and safety of certolizumab pegol induction therapy in an unselected Crohnʼs disease population","year":2009,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Science Foundation","keywords":"Medicine; Certolizumab pegol; Adalimumab; Adverse effect; Internal medicine; Crohn's disease; Infliximab; Inflammatory bowel disease; Population; Maintenance therapy; Gastroenterology; Surgery; Disease; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000637735,0.0003346756,0.0003465084,0.0004051711,0.0004231699,0.0004130178,0.0001342857,0.0004058451,0.001313801],"category_scores_gemma":[0.001602505,0.0001379529,0.0002443656,0.0002887421,0.0003514306,0.0002271226,0.0001954791,0.0002996326,0.0002654076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003019025,"about_ca_system_score_gemma":0.0003008973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001091163,"about_ca_topic_score_gemma":0.001200804,"domain_scores_codex":[0.9996283,0.0001440861,0.00002634316,0.0000805115,0.0000684472,0.00005236445],"domain_scores_gemma":[0.9991913,0.0002282491,0.000279995,0.00004228982,0.00005879277,0.0001992018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.002356302,0.0005915274,0.987834,0.00002321188,0.00006011633,0.0007114492,0.0001954604,0.0001163718,0.001746843,0.0000130396,0.0002258952,0.006125866],"study_design_scores_gemma":[0.0003256743,0.005176472,0.9917222,0.000007476681,0.00006011508,0.001621201,0.0001511299,0.0003880453,0.0002336082,0.00002148676,0.0002852695,0.000007436865],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997308,0.00008799609,0.00001602768,0.00001940367,0.000001303719,0.000006855813,0.00003449367,0.000001557206,0.000101512],"genre_scores_gemma":[0.9996139,0.00006722016,0.00003879534,0.00004250036,0.00001493632,0.00001068386,0.0001582378,9.667203e-7,0.0000528045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313801,"threshold_uncertainty_score":0.004395127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008530561082022034,"score_gpt":0.249763386874336,"score_spread":0.241232825792314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}