{"id":"W1988012657","doi":"10.1210/me.2002-0120","title":"Bile Acids Induce the Expression of the Human Peroxisome Proliferator-Activated Receptor α Gene via Activation of the Farnesoid X Receptor","year":2003,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":484,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"School of Medicine, New York University; York University","keywords":"Farnesoid X receptor; Chenodeoxycholic acid; Nuclear receptor; Biology; Peroxisome proliferator-activated receptor; Bile acid; Constitutive androstane receptor; Retinoid X receptor alpha; Retinoid X receptor; CYP8B1; G protein-coupled bile acid receptor; Liver X receptor; Peroxisome proliferator-activated receptor alpha; Small heterodimer partner; Cholic acid; Receptor; Nuclear receptor coactivator 1; Response element; Endocrinology; Biochemistry; Promoter; Gene expression; Transcription factor; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199649507728922,"score_gpt":0.2411323070190382,"score_spread":0.2291358119417489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}