{"id":"W1988025623","doi":"10.1002/hep.23743","title":"Phase 1b Study of Pegylated Interferon Lambda 1 With or Without Ribavirin in Patients with Chronic Genotype 1 Hepatitis C Virus Infection†","year":2010,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Gilead Sciences; GlaxoSmithKline; Valeant Pharmaceuticals International; Pfizer; Bristol-Myers Squibb","keywords":"Ribavirin; Pegylated interferon; Virology; Medicine; Genotype; Chronic hepatitis; Interferon; Hepatitis C virus; Virus; Immunology; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001948448,0.001647324,0.001936826,0.0002745384,0.0005770439,0.0007351289,0.0007683416,0.001228571,0.003607754],"category_scores_gemma":[0.0007644974,0.0006029658,0.001008773,0.0002798028,0.0009379095,0.0006843875,0.0003270884,0.002827442,0.0009690639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008217985,"about_ca_system_score_gemma":0.002188111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012764,"about_ca_topic_score_gemma":0.001975068,"domain_scores_codex":[0.999472,0.0002876296,0.00002424079,0.00007653487,0.00003475004,0.0001049167],"domain_scores_gemma":[0.9993384,0.0001237793,0.0001109284,0.00004232481,0.000043192,0.0003412267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7870779,0.08078164,0.01062051,0.0005966226,0.0007239665,0.0002855378,0.0003653463,0.001327288,0.03737944,0.0001682672,0.003398502,0.07727494],"study_design_scores_gemma":[0.5585659,0.4249801,0.01056013,0.00002944679,0.0002148307,0.0001942876,0.00005113438,0.0006594227,0.002718722,0.00007593988,0.001928709,0.00002136334],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993433,0.001321371,0.0004898599,0.0005016359,0.0001292924,0.002499482,0.0005827022,0.00007263162,0.0009699624],"genre_scores_gemma":[0.9891781,0.001006152,0.001642537,0.001210448,0.0001922614,0.003497174,0.001380855,0.00003016779,0.001862296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003607754,"threshold_uncertainty_score":0.01206911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02160913550248398,"score_gpt":0.3372636163729356,"score_spread":0.3156544808704516,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}