{"id":"W1988037222","doi":"10.1128/jvi.00121-11","title":"Passive Immunotherapies Protect WRvFire and IHD-J-Luc Vaccinia Virus-Infected Mice from Lethality by Reducing Viral Loads in the Upper Respiratory Tract and Internal Organs","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; U.S. Public Health Service; Symphogen; U.S. Department of Health and Human Services","keywords":"Vaccinia; Biology; Virology; Virus; Poxviridae; Orthopoxvirus; Antibody; Bioluminescence imaging; Plaque-forming unit; Spleen; Viral replication; Modified vaccinia Ankara; Viral load; Respiratory tract; Immunology; Recombinant DNA; Respiratory system; Luciferase; Cell culture; Transfection","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002625308,0.0009529504,0.0005431209,0.0004773021,0.0001363829,0.000270122,0.0003650171,0.0005732619,0.001068773],"category_scores_gemma":[0.00009867781,0.000211851,0.0005063815,0.0001347327,0.0003783393,0.000279746,0.0002020847,0.001133249,0.0003482941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002380544,"about_ca_system_score_gemma":0.0002159233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003557015,"about_ca_topic_score_gemma":0.0003850545,"domain_scores_codex":[0.9997156,0.00002983692,0.0000219427,0.0000801881,0.00004482125,0.0001075937],"domain_scores_gemma":[0.9998579,0.00002167224,0.00004595112,0.00002007911,0.00001360823,0.00004078758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002141878,0.0001338907,0.00008077733,0.0000214751,0.000003336337,0.00001205641,0.00001229384,0.00003675879,0.9987674,0.00004456304,0.00001706413,0.0006562965],"study_design_scores_gemma":[0.00002994796,0.002478248,0.002036185,0.000004733956,0.00001501047,0.0000890946,0.00001555481,0.000348875,0.9944277,0.00002346745,0.0005271275,0.000004033443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942386,0.0005773788,0.003448569,0.00004730897,0.00003950548,0.0001182485,0.0004720207,0.0001496125,0.0009087472],"genre_scores_gemma":[0.9871153,0.0006688292,0.006133926,0.00006917888,0.00002902492,0.0002748332,0.0009717163,0.00005883522,0.004678483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001068773,"threshold_uncertainty_score":0.003575385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647348100535656,"score_gpt":0.2571796227342758,"score_spread":0.2407061417289192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}