{"id":"W1988188164","doi":"10.1359/jbmr.2001.16.10.1837","title":"Accelerated Up-Regulation of L-Sox5, Sox6, and Sox9 by BMP-2 Gene Transfer During Murine Fracture Healing","year":2001,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chondrogenesis; SOX9; Cell biology; Chondrocyte; Bone morphogenetic protein 2; Type II collagen; RUNX2; Chemistry; Bone morphogenetic protein; In situ hybridization; Transcription factor; Bone healing; Mesenchymal stem cell; Cartilage; Molecular biology; Biology; Gene expression; Anatomy; Gene; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009179726,0.0001288547,0.0002622453,0.0002605922,0.0001230985,0.00005829847,0.00009758618,0.0002016653,0.00004748371],"category_scores_gemma":[0.0001189839,0.0001118416,0.00007951066,0.0002366266,0.0001135526,0.00002510638,0.00008436037,0.0004656219,4.078152e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000030592,"about_ca_system_score_gemma":0.0001451073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009874525,"about_ca_topic_score_gemma":0.00002891615,"domain_scores_codex":[0.9982865,0.0001503913,0.0004197296,0.0002248435,0.0005573155,0.000361231],"domain_scores_gemma":[0.9989479,0.00002444228,0.00008032692,0.0001556646,0.000586407,0.0002052481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009990233,0.00005994472,0.0001148132,0.00005736084,0.00007929268,0.00003304975,0.00007563119,0.0001569013,0.9948028,0.000008876602,0.001359627,0.00225266],"study_design_scores_gemma":[0.002174018,0.0007641105,0.002072885,0.00006423632,0.00001641015,0.0004284692,0.00008599748,0.0001591132,0.986868,0.00006437291,0.007187194,0.0001151714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889324,0.00711876,0.002868677,0.0008085429,0.00003967941,0.0001626437,0.00001014655,0.000002101915,0.00005709192],"genre_scores_gemma":[0.990292,0.007273156,0.0001944069,0.00004797712,0.0002280342,0.000003907674,0.00002868273,0.0000246881,0.001907223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007934798,"threshold_uncertainty_score":0.4560769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02947220152999827,"score_gpt":0.333509721330883,"score_spread":0.3040375198008848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}