{"id":"W1988209640","doi":"10.1371/journal.pone.0043684","title":"Pharmacokinetics of Peptide Mediated Delivery of Anticancer Drug Ellipticine","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"School of Medicine, Shanghai Jiao Tong University; Shanghai Jiao Tong University; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Pharmacokinetics; Bioavailability; In vivo; Chemistry; Peptide; Pharmacology; High-performance liquid chromatography; Chromatography; Biochemistry; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442399,0.0001406194,0.0001937315,0.0001017799,0.00005353568,0.00016315,0.000094227,0.0001896572,0.0005907059],"category_scores_gemma":[0.0003082232,0.0001050939,0.00009134397,0.00008060794,0.0001759448,0.0002610868,0.00006222197,0.0003860065,0.0001499224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002793819,"about_ca_system_score_gemma":0.0001743655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004282821,"about_ca_topic_score_gemma":0.0002962922,"domain_scores_codex":[0.99992,0.00002152905,0.000003663975,0.00001958173,0.00001752576,0.00001760871],"domain_scores_gemma":[0.9999223,0.00001953998,0.00002600638,0.000006762757,0.00001064318,0.0000147976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002767506,0.000136734,0.0008276756,0.00003463563,0.00001183641,0.00006402021,0.00003888069,0.0005750286,0.9897828,0.0001003947,0.00009958611,0.005560971],"study_design_scores_gemma":[0.0001438848,0.009740218,0.01536618,0.000005756024,0.00004870493,0.0003211887,0.00004209357,0.008912653,0.9628518,0.00009929251,0.002450381,0.00001792729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974256,0.0006158212,0.001336494,0.00002635615,0.00001014916,0.00001837725,0.00008789615,0.00002280791,0.0004566311],"genre_scores_gemma":[0.997722,0.0003408344,0.0006634219,0.00002098383,0.000008581198,0.00003203187,0.0001332395,0.000009758944,0.001069237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005907059,"threshold_uncertainty_score":0.002027094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02961180587414464,"score_gpt":0.2457288932451662,"score_spread":0.2161170873710216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}