{"id":"W1988276243","doi":"10.1021/ja063071s","title":"A <sup>2</sup>H NMR Relaxation Experiment for the Measurement of the Time Scale of Methyl Side-Chain Dynamics in Large Proteins","year":2006,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Isotopomers; Side chain; Relaxation (psychology); Protein dynamics; Dynamics (music); Methyl group; Molecular dynamics; Analytical Chemistry (journal); Nuclear magnetic resonance; Computational chemistry; Molecule; Chromatography; Physics; Organic chemistry; Group (periodic table)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006997031,0.0001184986,0.000249586,0.000008868687,0.00006021744,0.000006411859,0.0004407717,0.00008122037,0.000001652399],"category_scores_gemma":[0.000149838,0.00006080111,0.0005404646,0.0001710076,0.0002727895,0.000004127252,0.0001484509,0.0001893891,6.28976e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001821005,"about_ca_system_score_gemma":0.0001190471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008457346,"about_ca_topic_score_gemma":0.00002164711,"domain_scores_codex":[0.9988099,0.00007263695,0.000445925,0.0001203106,0.0003775937,0.0001736041],"domain_scores_gemma":[0.9985521,0.0000398825,0.0008694333,0.0003059868,0.0002085035,0.00002402141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001282631,0.0001047343,0.0009864214,0.0000164728,0.00008719513,5.159928e-8,0.0001646624,0.001858586,0.9955426,0.00006136761,0.0004971732,0.0005524593],"study_design_scores_gemma":[0.0006903,0.0001465478,0.00122151,0.00004383913,0.00006277641,0.000006234815,0.0006600904,0.01399901,0.9816449,0.0008497698,0.0005827487,0.00009231019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918356,0.0004108294,0.006150091,0.00107364,0.00002485423,0.0004207343,0.00002993274,0.0000014442,0.00005290168],"genre_scores_gemma":[0.9959167,0.0000302326,0.003647807,0.0002057578,0.0001251598,0.00001912974,0.000004061724,0.00001322056,0.00003794421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01389775,"threshold_uncertainty_score":0.2479397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00535263681285251,"score_gpt":0.2304708195427651,"score_spread":0.2251181827299126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}