{"id":"W1988286071","doi":"10.1111/bjh.12262","title":"Gene methylation and silencing of <i><scp>SOCS</scp>3</i> in mantle cell lymphoma","year":2013,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Mantle cell lymphoma; Cyclin D1; Gene silencing; Methylation; Biology; Cancer research; Cell culture; Cell growth; Molecular biology; Cell; Cell cycle; Lymphoma; Gene; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002221574,0.00007343176,0.0004647357,0.0001994395,0.00002948234,0.00001590097,0.00005199236,0.00008487397,0.00007750101],"category_scores_gemma":[0.0002602122,0.00007738735,0.0000826176,0.0001112173,0.00005541618,0.0001598375,0.0000225126,0.0001635734,0.000007240762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002705741,"about_ca_system_score_gemma":0.00007325759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005691409,"about_ca_topic_score_gemma":0.00004083535,"domain_scores_codex":[0.9989761,0.00006418373,0.0005858377,0.00009720063,0.0001263529,0.0001503941],"domain_scores_gemma":[0.9990464,0.0002082744,0.000359606,0.00006711665,0.0002355937,0.00008294106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002300232,0.0005230763,0.01199546,0.0002828234,0.0000787255,0.005658789,0.0007063383,0.00003225047,0.9464192,0.00007444719,0.006471606,0.02773424],"study_design_scores_gemma":[0.003457044,0.0003866551,0.03887919,0.0007933212,0.00009337018,0.2004362,0.001111081,0.0004017444,0.7526116,0.0006329046,0.001136869,0.00006004567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936933,0.004411536,0.0003614628,0.0001443653,0.0001637159,0.0001103586,0.00000384029,0.000004984776,0.001106428],"genre_scores_gemma":[0.9969749,0.0006619039,0.002071755,0.0001219658,0.00006341259,0.000002904099,0.000002607273,0.00001193566,0.00008861806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1947774,"threshold_uncertainty_score":0.3155765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138169572655806,"score_gpt":0.2389984475711404,"score_spread":0.2276167518445824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}