{"id":"W1988289925","doi":"10.1097/01.mop.0000187191.74295.97","title":"Advances in overgrowth syndromes: clinical classification to molecular delineation in Sotos syndrome and Beckwith-Wiedemann syndrome","year":2005,"lang":"en","type":"review","venue":"Current Opinion in Pediatrics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Genetics; SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Sotos syndrome; Medicine; Bioinformatics; Pediatrics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001019831,0.000592908,0.001325262,0.000926897,0.00003743222,0.00005742085,0.0004466233,0.0007207722,0.000006809029],"category_scores_gemma":[0.0005339671,0.0006105942,0.0002640532,0.00108293,0.00005691882,0.00002739819,0.0003580784,0.000648592,0.00002845727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001485773,"about_ca_system_score_gemma":0.0003341764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001021729,"about_ca_topic_score_gemma":0.00002065992,"domain_scores_codex":[0.9953775,0.0003656253,0.002031791,0.00129858,0.0003445008,0.0005820142],"domain_scores_gemma":[0.9984777,0.0001053723,0.0005559984,0.0005727551,0.00007403476,0.0002141384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007903558,0.0003044534,0.02171083,0.007197165,0.00001357435,0.00001313935,0.00002670298,0.0001271502,0.000002458489,0.00004851351,0.000103585,0.9704445],"study_design_scores_gemma":[0.001165473,0.000636206,0.03414715,0.007088439,0.000108697,0.0005811073,0.0000547117,0.0002520883,4.739651e-7,0.00004549142,0.9547368,0.001183343],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03212468,0.9634108,0.0008922963,0.00003553654,0.001961353,0.00149239,0.00003978156,0.00001426056,0.00002892173],"genre_scores_gemma":[0.01282428,0.9850213,0.0006777708,0.00001820727,0.0003920566,0.0003407031,0.0006349228,0.00007608463,0.00001467385],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9692612,"threshold_uncertainty_score":0.9996346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08456372896538565,"score_gpt":0.4209877559415565,"score_spread":0.3364240269761708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}