{"id":"W1988323530","doi":"10.1139/w08-125","title":"Sequencing and modular analysis of the hybrid non-ribosomal peptide synthase – polyketide synthase gene cluster from the marine sponge <i>Hymeniacidon perleve</i>-associated bacterium <i>Pseudoalteromonas</i> sp. strain NJ631","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Program for Changjiang Scholars and Innovative Research Team in University; National High-tech Research and Development Program","keywords":"ORFS; Biology; Polyketide synthase; Open reading frame; Gene cluster; Adenylylation; Biochemistry; Gene; Amino acid; Polyketide; Ribosomal RNA; Peptide sequence; Genetics; Biosynthesis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000947084,0.0003832385,0.0002974623,0.000361892,0.0001556714,0.0002645451,0.0002077741,0.0002354407,0.0004449579],"category_scores_gemma":[0.0002831989,0.0001432222,0.0005732622,0.0004497144,0.0001525941,0.0001717449,0.0002491156,0.0003011138,0.0004528439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002172395,"about_ca_system_score_gemma":0.0003116671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00142531,"about_ca_topic_score_gemma":0.001567031,"domain_scores_codex":[0.9998882,0.000009410845,0.00001078289,0.0000327399,0.00003891324,0.00002001756],"domain_scores_gemma":[0.9997548,0.00003917258,0.0000693351,0.00002395887,0.00004530974,0.00006741519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001085236,0.00002420775,0.001274287,0.00007485059,0.000007697854,0.0001655843,0.0001023893,0.00006000572,0.9962721,0.0000314964,0.00001725861,0.001861494],"study_design_scores_gemma":[0.0001066213,0.001080118,0.3417453,0.0000619924,0.0003475855,0.003712073,0.001096977,0.002585026,0.6407694,0.0003734401,0.00805702,0.00006451319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949951,0.0003770459,0.002389072,0.00006254371,0.00001420929,0.00005104747,0.001538295,0.00002925718,0.0005433636],"genre_scores_gemma":[0.9759237,0.0007106914,0.009086758,0.0001109307,0.00002582352,0.0001060987,0.01192618,0.00005342818,0.002056319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00142531,"threshold_uncertainty_score":0.002834082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00886570154942488,"score_gpt":0.2013493136567883,"score_spread":0.1924836121073635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}