{"id":"W1988337569","doi":"10.1371/journal.pone.0026381","title":"Targeted Cell Fusion Facilitates Stable Heterokaryon Generation In Vitro and In Vivo","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Muscular Dystrophy Canada; Stem Cell Network","keywords":"Reprogramming; Cell fusion; Cell biology; In vivo; Chromatin; Biology; Heterokaryon; Cell; Cancer research; Biochemistry; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003376806,0.0002883465,0.0002783487,0.0002411774,0.0002032972,0.000356965,0.0003177765,0.0004539789,0.001413483],"category_scores_gemma":[0.0001681834,0.0002072771,0.0002499345,0.0001412165,0.0003288886,0.0002338659,0.0004792573,0.0007389442,0.0007326677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002363904,"about_ca_system_score_gemma":0.0001893201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003002363,"about_ca_topic_score_gemma":0.0005787864,"domain_scores_codex":[0.9997448,0.00004691276,0.00002175318,0.00006891797,0.00007858544,0.00003898856],"domain_scores_gemma":[0.9998344,0.00005135811,0.00003766696,0.00003776083,0.0000141627,0.00002452862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002291738,0.000008067307,0.00003602571,0.00001222918,0.000002051971,0.00002256503,0.00001526427,0.00006320062,0.9985618,0.0003538499,0.00002143929,0.0008805702],"study_design_scores_gemma":[0.000006762787,0.00007372736,0.0003650876,0.000002312161,0.000005333182,0.0001549535,0.000007830417,0.0006419977,0.9966042,0.00006308442,0.002072494,0.000002287028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8625624,0.002427072,0.1240993,0.0002181774,0.0001062112,0.0001960289,0.0007678734,0.0006171357,0.009005853],"genre_scores_gemma":[0.97303,0.0008630466,0.02108308,0.00004276037,0.00001296407,0.00008516071,0.0006396073,0.0001146206,0.004128788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001413483,"threshold_uncertainty_score":0.004728615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04718550602981575,"score_gpt":0.2422620566757115,"score_spread":0.1950765506458957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}