{"id":"W1988453500","doi":"10.1016/j.crvi.2004.10.013","title":"Molecular biology and genetics of Alzheimer's disease","year":2005,"lang":"en","type":"review","venue":"Comptes Rendus Biologies","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Presenilin; Disease; Apolipoprotein E; Alzheimer's disease; Amyloid precursor protein; Biology; Gene; Genetics; Dementia; Molecular genetics; Amyloid (mycology); Neuroscience; Bioinformatics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005388383,0.001149833,0.001578899,0.002011105,0.000338522,0.001050484,0.0009495214,0.00115249,0.002825743],"category_scores_gemma":[0.0005427695,0.0002778195,0.000339787,0.002220477,0.0009518797,0.001480318,0.0006336609,0.001805872,0.003363856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001153229,"about_ca_system_score_gemma":0.001213901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001615141,"about_ca_topic_score_gemma":0.002173017,"domain_scores_codex":[0.9998196,0.00003323414,0.00002099188,0.00003042607,0.00007980307,0.00001593654],"domain_scores_gemma":[0.9997861,0.00007002753,0.00002738368,0.00001241264,0.00007583669,0.00002826711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007183971,0.00007676914,0.000309524,0.007284737,0.0000689852,0.0004280735,0.00007153759,0.0004869145,0.002695547,0.007631507,0.05417709,0.9266974],"study_design_scores_gemma":[0.00001514958,0.00003219944,0.0009441759,0.001393578,0.00003568484,0.001893905,0.00004159585,0.00005861129,0.0003302387,0.00493313,0.9903093,0.00001244469],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006825731,0.9981516,0.0001051867,0.0002358701,0.0002374684,0.00000283201,0.000005865309,0.000005255693,0.001187687],"genre_scores_gemma":[0.000469395,0.9982691,0.0001131297,0.0001332615,0.0001763824,0.000003358391,0.00001231571,8.501472e-7,0.0008222436],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002825743,"threshold_uncertainty_score":0.009453058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1103344500328277,"score_gpt":0.4242427225380236,"score_spread":0.313908272505196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}