{"id":"W1988486780","doi":"10.1038/cgt.2011.18","title":"Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8+ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice","year":2011,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"Cytotoxic T cell; Immunology; CTL*; Immunotherapy; CD8; HER2/neu; Cancer research; Antibody; Immune system; Antigen; Adjuvant; Biology; Medicine; Cancer; Breast cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004044462,0.0006846038,0.0005976181,0.0005409414,0.0001624547,0.0003698469,0.0004174212,0.0005318517,0.001480452],"category_scores_gemma":[0.0003374512,0.0002631086,0.000401749,0.000200134,0.0003476599,0.0003891159,0.0002041264,0.001317048,0.0002916268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003222807,"about_ca_system_score_gemma":0.0005951934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009716405,"about_ca_topic_score_gemma":0.001255125,"domain_scores_codex":[0.9997144,0.00006178663,0.00002488495,0.00004178453,0.00004487535,0.000112131],"domain_scores_gemma":[0.9996203,0.0001312432,0.0000606117,0.00004464754,0.0000215537,0.0001215754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002444646,0.0008721582,0.0001334489,0.00004352691,0.0000110706,0.00007504439,0.00004147564,0.0003162173,0.9930768,0.0002844557,0.00007153251,0.002629609],"study_design_scores_gemma":[0.0003732847,0.003546342,0.0008039924,0.000008692389,0.00004656791,0.0001034853,0.00001747508,0.001956408,0.9923109,0.0001002187,0.0007257854,0.00000680166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968873,0.0005999138,0.001102861,0.00007897767,0.00008640464,0.00005585399,0.0001871279,0.0001125067,0.0008890938],"genre_scores_gemma":[0.9951928,0.0003997585,0.001347605,0.00005475468,0.00004463664,0.00005557908,0.0002938224,0.00003217861,0.002578881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001480452,"threshold_uncertainty_score":0.00495261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03215954182566027,"score_gpt":0.3251027456786804,"score_spread":0.2929432038530201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}