{"id":"W1988596049","doi":"10.1002/jps.1083","title":"Cyclosporine A transfer between high‐ and low‐density lipoproteins: Independent from lipid transfer protein I‐facilitated transfer of lipoprotein‐coated phospholipids because of high affinity of cyclosporine a for the protein component of lipoproteins","year":2001,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Plant lipid transfer proteins; Chemistry; Lipoprotein; Phospholipid transfer protein; Phospholipid; High-density lipoprotein; Apolipoprotein B; Lecithin; Low-density lipoprotein; Biochemistry; Cholesterol; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003841571,0.0003792152,0.0003565265,0.0002587432,0.0004224992,0.0008347454,0.0004027693,0.0004292901,0.00116648],"category_scores_gemma":[0.000434435,0.0002431371,0.0003599658,0.0001887355,0.0006176258,0.0005376944,0.0004624792,0.0008781943,0.0005108134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006294984,"about_ca_system_score_gemma":0.0004948642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006529133,"about_ca_topic_score_gemma":0.0005114772,"domain_scores_codex":[0.9997134,0.00008618411,0.00001577389,0.00003780173,0.00005642635,0.00009058526],"domain_scores_gemma":[0.9995236,0.0001522229,0.0001028027,0.00008931228,0.00004004518,0.00009199185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006306812,0.00007033024,0.0003821468,0.00004784844,0.00001909918,0.0001301096,0.00003852478,0.00007793234,0.9952378,0.001079813,0.00006142115,0.002224308],"study_design_scores_gemma":[0.00008971847,0.0002151914,0.002134883,0.00000402083,0.00002796972,0.000242178,0.00001471185,0.0008760443,0.9956118,0.0001264053,0.000652437,0.000004517301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935267,0.001219705,0.003173582,0.0001226326,0.00003085251,0.00003579422,0.00004195653,0.00007179358,0.001777068],"genre_scores_gemma":[0.9980258,0.000286161,0.0007875848,0.00002462586,0.00001208958,0.00001198297,0.00004968747,0.0000169125,0.0007852558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00116648,"threshold_uncertainty_score":0.004567385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04995573517729105,"score_gpt":0.3326791033032593,"score_spread":0.2827233681259682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}