{"id":"W1988685629","doi":"10.1016/j.ydbio.2005.03.001","title":"Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction","year":2005,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":177,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Ligue Contre le Cancer","keywords":"Biology; Cell biology; Blastomere; Embryo; Blastocyst; Caenorhabditis elegans; Drosophila melanogaster; Oocyte; Cell fate determination; Morphogenesis; Embryonic stem cell; Cytoplasm; Gastrulation; Embryogenesis; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002267632,0.0002294312,0.000311182,0.0006987659,0.0002989672,0.0008673291,0.0002930081,0.000473106,0.001861945],"category_scores_gemma":[0.0003491797,0.0005224775,0.0002441094,0.0002824921,0.0003341228,0.0005884627,0.0004306037,0.000898377,0.001338211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004569416,"about_ca_system_score_gemma":0.0001920538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000693818,"about_ca_topic_score_gemma":0.001216763,"domain_scores_codex":[0.9998004,0.00001936258,0.00001051295,0.00004569873,0.00007001544,0.00005411086],"domain_scores_gemma":[0.9996513,0.00005893214,0.0001188593,0.00003229079,0.00005841934,0.00008021422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001996257,0.0000100674,0.001924347,0.00003309585,0.00000637738,0.0002898369,0.00007822995,0.000107211,0.9933146,0.001240786,0.0001777088,0.002618066],"study_design_scores_gemma":[0.00004405323,0.0001597274,0.1695793,0.00005183418,0.00003087498,0.00101259,0.0002041421,0.001367927,0.8166384,0.0005828266,0.01030701,0.00002117612],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843915,0.00308644,0.006261881,0.0001308081,0.00003205661,0.00001660465,0.0003843367,0.0001770838,0.005519249],"genre_scores_gemma":[0.9892992,0.0008775605,0.001974752,0.00009197531,0.00002685028,0.00003336116,0.000494675,0.00008856339,0.007112994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001861945,"threshold_uncertainty_score":0.006228864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009104483167442797,"score_gpt":0.2324095327987768,"score_spread":0.223305049631334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}