{"id":"W1988726471","doi":"10.4161/onci.1.2.18458","title":"FIST, a sword and shield fusokine for cancer immunotherapy","year":2012,"lang":"en","type":"article","venue":"OncoImmunology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Occupational Cancer Research Centre","funders":"","keywords":"Fist; Ectodomain; Cancer research; Immunotherapy; Cancer immunotherapy; Angiogenesis; Immune system; Medicine; Receptor; Fusion protein; Immunology; Biology; Internal medicine; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001842694,0.0004414172,0.0002172397,0.0004133597,0.0001624858,0.0002782712,0.0001775028,0.0004019222,0.001487831],"category_scores_gemma":[0.0000982089,0.00008384463,0.0003021623,0.0001749607,0.0002400198,0.000249884,0.0002858047,0.0007083123,0.000514366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002626392,"about_ca_system_score_gemma":0.0003344338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001927182,"about_ca_topic_score_gemma":0.0003612422,"domain_scores_codex":[0.9999337,0.00001521221,0.000004579965,0.00001127515,0.00002098376,0.0000142705],"domain_scores_gemma":[0.9999313,0.0000137639,0.00001388001,0.000008381107,0.00000664489,0.00002597415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003163224,0.00008376436,0.0002730078,0.0001080686,0.00001516719,0.0002980162,0.00002246422,0.0004883764,0.9682833,0.00297477,0.0009396457,0.02619729],"study_design_scores_gemma":[0.000225784,0.001748132,0.001347466,0.00003457316,0.00007069712,0.002890444,0.00002327982,0.001448111,0.9136779,0.001029401,0.07748599,0.0000182568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8500872,0.06233888,0.05742411,0.002707419,0.001014969,0.000374422,0.001097403,0.0009055556,0.02404995],"genre_scores_gemma":[0.9555818,0.01331796,0.01894111,0.000453928,0.000177991,0.000134761,0.0008997394,0.00003337272,0.0104593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001487831,"threshold_uncertainty_score":0.004977286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438153272747668,"score_gpt":0.2964366606507601,"score_spread":0.2820551279232834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}