{"id":"W1988726471","doi":"10.4161/onci.1.2.18458","title":"FIST, a sword and shield fusokine for cancer immunotherapy","year":2012,"lang":"en","type":"article","venue":"OncoImmunology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Occupational Cancer Research Centre","funders":"","keywords":"Fist; Ectodomain; Cancer research; Immunotherapy; Cancer immunotherapy; Angiogenesis; Immune system; Medicine; Receptor; Fusion protein; Immunology; Biology; Internal medicine; Recombinant DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001091281,0.0001369256,0.000153538,0.00003127728,0.00007114709,0.00001005326,0.0001388114,0.0001777273,0.00006235445],"category_scores_gemma":[0.00005305466,0.0001305843,0.00006144534,0.00003522518,0.0001213726,0.000004505388,0.00006938264,0.00006354532,0.000004449372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000014806,"about_ca_system_score_gemma":0.00005918508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004178364,"about_ca_topic_score_gemma":0.00003090438,"domain_scores_codex":[0.9992362,0.0000355187,0.000147859,0.000204923,0.00004021988,0.0003352522],"domain_scores_gemma":[0.9995481,0.0000339076,0.00006644593,0.0002636635,0.00003754647,0.00005037486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004793902,0.0001361216,0.0153858,0.00002365878,0.0001975924,4.674612e-7,0.0002186293,0.00000332632,0.9504907,0.0002675416,0.002428806,0.03036802],"study_design_scores_gemma":[0.001231801,0.0003147612,0.02398549,0.00001390958,0.00002861385,0.00001672046,0.00007902293,0.000005065112,0.1882016,0.00007997478,0.7858049,0.0002381668],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9437261,0.05392035,0.001102723,0.0003076122,0.0003942981,0.0002023789,0.00003051813,0.00003117044,0.0002848078],"genre_scores_gemma":[0.9957009,0.0009814278,0.0009433532,0.0006218389,0.0004552644,0.0002107418,0.00006648006,0.00004461191,0.0009753673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7833761,"threshold_uncertainty_score":0.5325075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438153272747668,"score_gpt":0.2964366606507601,"score_spread":0.2820551279232834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}