{"id":"W1988732672","doi":"10.1139/o09-058","title":"Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells","year":2009,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Korea Science and Engineering Foundation","keywords":"FADD; Apoptosis; Cancer research; Tumor necrosis factor alpha; Protein kinase B; Caspase 8; Death domain; Inhibitor of apoptosis domain; XIAP; Chemistry; Caspase; Cancer cell; Biology; Cell biology; Programmed cell death; Immunology; Cancer; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005343861,0.000174931,0.0002303556,0.0001303786,0.0001320782,0.0001895203,0.0001351061,0.0001585582,0.001548429],"category_scores_gemma":[0.000106396,0.00008914389,0.0001532241,0.00008286869,0.00009765876,0.00009481928,0.0001129864,0.0004249997,0.0003991321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003491118,"about_ca_system_score_gemma":0.0002290485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002587086,"about_ca_topic_score_gemma":0.00414263,"domain_scores_codex":[0.9999274,0.00001106896,0.000003747194,0.00001255278,0.00002454054,0.00002068569],"domain_scores_gemma":[0.9999672,0.000006005188,0.00000659558,0.000003818288,0.000006749922,0.000009568245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008440309,0.00003229005,0.0001455604,0.00002456725,0.00000302251,0.00004326259,0.000005899441,0.00002299546,0.998487,0.00005797622,0.0001084039,0.0009846537],"study_design_scores_gemma":[0.0001002316,0.0003300469,0.007461899,0.000007081533,0.00002061143,0.0003485681,0.00001723185,0.001410301,0.9831733,0.00007684157,0.007049914,0.000004038116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865875,0.005296123,0.001761832,0.0003766376,0.00008261212,0.00006697973,0.0004291875,0.000107585,0.005291683],"genre_scores_gemma":[0.9939253,0.001249857,0.0008602209,0.00008427324,0.00002018505,0.00003319271,0.0005002125,0.00001093375,0.00331596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002587086,"threshold_uncertainty_score":0.005180061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006346511128135167,"score_gpt":0.2484895441044202,"score_spread":0.242143032976285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}