{"id":"W1988740497","doi":"10.1038/sj.onc.1207108","title":"Regulation of apoptosis by endoplasmic reticulum pathways","year":2003,"lang":"en","type":"review","venue":"Oncogene","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":736,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Cell biology; Biology; Endoplasmic reticulum; Programmed cell death; Mitochondrion; Apoptosis; Crosstalk; Caspase; Signal transduction; Unfolded protein response; Cytosol; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007167301,0.001419973,0.001997451,0.001803858,0.0003925159,0.001386423,0.001590573,0.001290072,0.001818525],"category_scores_gemma":[0.0005120558,0.0003516189,0.0003601766,0.002293931,0.0008972911,0.001663554,0.0006960283,0.002539362,0.002383763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001132343,"about_ca_system_score_gemma":0.0008615649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009883784,"about_ca_topic_score_gemma":0.001696725,"domain_scores_codex":[0.9997737,0.0000271141,0.00002988143,0.00004583674,0.00009493464,0.00002849656],"domain_scores_gemma":[0.9996982,0.00009727569,0.00003853018,0.00001600364,0.0001182248,0.00003185247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001976927,0.0000915634,0.0002145266,0.007552115,0.00008000297,0.0005847274,0.00006586265,0.0008040451,0.009857398,0.008680383,0.03467937,0.9371923],"study_design_scores_gemma":[0.0000426685,0.00006530076,0.0006914674,0.001066896,0.00008605245,0.001773297,0.00006172602,0.0001763869,0.00371659,0.004493204,0.9878015,0.00002492594],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002456477,0.9959722,0.0008387134,0.0003840737,0.0005929956,0.000007752352,0.00002216009,0.00002596459,0.001910392],"genre_scores_gemma":[0.001163931,0.9963222,0.0005144757,0.0002359166,0.0002826337,0.00001072776,0.00003781305,0.000002721304,0.001429703],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001997451,"threshold_uncertainty_score":0.008215725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02062509755067075,"score_gpt":0.2639501692907081,"score_spread":0.2433250717400373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}