{"id":"W1988753673","doi":"10.1016/j.jmb.2008.08.027","title":"CRP Binding and Transcription Activation at CRP-S Sites","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; University of British Columbia","keywords":"Promoter; Binding site; Consensus sequence; Biology; Haemophilus influenzae; DNA binding site; Base pair; Transcription (linguistics); Molecular biology; DNA; Conserved sequence; DNA-binding protein; Transcription factor; Genetics; Gene; Base sequence; Gene expression; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006267626,0.000577177,0.0004846187,0.0006897055,0.0009724518,0.001218412,0.0007206969,0.001093797,0.01032821],"category_scores_gemma":[0.001148697,0.0006855002,0.0008589739,0.0004474977,0.0009662971,0.0005757306,0.0009073474,0.001495633,0.003190402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001270826,"about_ca_system_score_gemma":0.0009255943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004306224,"about_ca_topic_score_gemma":0.0046974,"domain_scores_codex":[0.9989844,0.0001963824,0.00003702885,0.0001443319,0.0002285008,0.0004092508],"domain_scores_gemma":[0.9989488,0.000406148,0.00007275162,0.0001060285,0.000160675,0.0003057403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001422716,0.0001255041,0.0005214517,0.00005837516,0.000006170701,0.0001012027,0.00008403473,0.0002261034,0.9927735,0.001561341,0.0003764095,0.002743289],"study_design_scores_gemma":[0.00009009857,0.0002165532,0.009241165,0.00002032399,0.000005634341,0.0001439676,0.0001415732,0.002130702,0.9847335,0.0006583714,0.002590769,0.00002724822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9760537,0.002554484,0.01074184,0.0009535454,0.0001549681,0.00007594049,0.0004704243,0.0003648252,0.008630256],"genre_scores_gemma":[0.9897436,0.0003325686,0.002277739,0.0002006343,0.00004987662,0.0000375971,0.0008299272,0.00006412608,0.006463908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01032821,"threshold_uncertainty_score":0.03455126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293047233406559,"score_gpt":0.2417093628116425,"score_spread":0.228778890477577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}