{"id":"W1988819052","doi":"10.1074/jbc.m206677200","title":"The Molecular Determinants of Ionic Regulatory Differences between Brain and Kidney Na+/Ca2+ Exchanger (NCX1) Isoforms","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Gene isoform; Sodium-calcium exchanger; Ionic bonding; Chemistry; Kidney; Biophysics; Neuroscience; Biochemistry; Internal medicine; Biology; Medicine; Gene; Ion; Intracellular; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130302,0.0001318522,0.00010583,0.0001057996,0.00007784727,0.0001667049,0.0001506608,0.0001919886,0.0008919478],"category_scores_gemma":[0.0001438268,0.00009445992,0.0001701996,0.00005370774,0.000186309,0.0001943436,0.0001679081,0.0003075037,0.0002228299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001260158,"about_ca_system_score_gemma":0.0001409309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002401609,"about_ca_topic_score_gemma":0.000294034,"domain_scores_codex":[0.9998975,0.00001264808,0.00001344774,0.00003584643,0.00001969748,0.00002093431],"domain_scores_gemma":[0.9998549,0.00002573871,0.00005182911,0.00001043261,0.00001472079,0.00004231447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008624204,0.000007973724,0.0002432022,0.000008721091,0.000002364426,0.00003718067,0.000006281962,0.00001012831,0.9990886,0.0000901072,0.000005102638,0.000414003],"study_design_scores_gemma":[0.00007920093,0.0003984621,0.08394282,0.00001139573,0.00003977117,0.001445663,0.00007604725,0.0008412655,0.910572,0.0003480377,0.002233234,0.0000121606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982153,0.0003966135,0.000815164,0.00003322116,0.0000104247,0.000006450258,0.00006175526,0.00000938226,0.0004517321],"genre_scores_gemma":[0.9968496,0.0003911923,0.00129014,0.00005712535,0.00001196326,0.00001554328,0.0003037878,0.000008803396,0.001071808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008919478,"threshold_uncertainty_score":0.002983868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0261044036392533,"score_gpt":0.2481860309352482,"score_spread":0.2220816272959949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}