{"id":"W1988854705","doi":"10.1016/j.cbi.2013.05.006","title":"Cytotoxic interaction between amiodarone and desethylamiodarone in human peripheral lung epithelial cells","year":2013,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Cytotoxicity; Lactate dehydrogenase; Cytotoxic T cell; Toxicity; Pharmacology; Lung; Metabolite; Amiodarone; Programmed cell death; Chemistry; Apoptosis; Medicine; In vitro; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003829247,0.0001957686,0.0004250969,0.0002539314,0.0003796794,0.0004204716,0.0002272309,0.0003406669,0.002328053],"category_scores_gemma":[0.0004631011,0.0002042499,0.0003653374,0.0004023726,0.0001805666,0.0002696277,0.0001928096,0.0004282333,0.0004248048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422587,"about_ca_system_score_gemma":0.0003083975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002256809,"about_ca_topic_score_gemma":0.002120046,"domain_scores_codex":[0.9994422,0.00024785,0.00004801141,0.00005792005,0.0001038625,0.0001001795],"domain_scores_gemma":[0.9996995,0.0001530353,0.0000254079,0.0000340739,0.00006143312,0.00002671462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002140227,0.0002056017,0.00266106,0.000229713,0.000065653,0.0004550316,0.0002226994,0.0006694227,0.9865051,0.0003167802,0.0003345416,0.006194234],"study_design_scores_gemma":[0.0001250369,0.004287667,0.03263296,0.00002475197,0.00007607409,0.000920839,0.0003699845,0.00301359,0.9552575,0.00009493477,0.003176489,0.00002026122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922161,0.003643082,0.0007818194,0.0001113414,0.00004622151,0.00003246691,0.0003811086,0.00002458545,0.002763143],"genre_scores_gemma":[0.9966696,0.0008667868,0.0004950214,0.00004655072,0.0000178936,0.0000282188,0.0003966581,0.000003946512,0.001475238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002328053,"threshold_uncertainty_score":0.007788062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0404444209080187,"score_gpt":0.3399915763231728,"score_spread":0.2995471554151541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}